Bases moleculares de los tumores odontogénicos benignos: revisión de la literatura en el contexto de la última clasificación de la Organización Mundial de la Salud

  • Felipe Martins Silveira Área de Patología Molecular Estomatológica, Facultad de Odontología, Universidad de la República http://orcid.org/0000-0001-9834-5194
  • Vanesa Pereira-Prado Área de Patología Molecular Estomatológica, Facultad de Odontología, Universidad de la República http://orcid.org/0000-0001-7747-6718
  • Ronell Bologna-Molina Área de Patología Molecular Estomatológica, Facultad de Odontología, Universidad de la República http://orcid.org/0000-0001-9755-4779
Palabras clave: Tumores odontogénicos, Patología molecular

Resumen

Los tumores odontogénicos (TOs) son un grupo heterogéneo de lesiones que incluyen hamartomas hasta neoplasias benignas o malignas. El presente estudio tuvo como objetivo revisar la literatura sobre los aspectos moleculares y genéticos de algunos TOs benignos. A partir de los estudios revisados, se apoya la idea de que las causas genéticas pueden tener un papel importante en la etiología y en la patogénesis de algunos TOs. Sin embargo, las investigaciones sobre el tema aún no permiten concluir de manera sólida los mecanismos definitivos involucrados en el desarrollo y en la progresión de los TOs. Se sugiere el desarrollo de más estudios moleculares y genéticos que evalúen muestras significativas de TOs para establecer su etiopatogenia, facilitar su proceso diagnóstico y enriquecer su abordaje terapéutico.

Citas

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imagen ilustrativa del artículo
Publicado
2022-02-24
Cómo citar
Silveira, F. M., Pereira-Prado, V., & Bologna-Molina, R. (2022). Bases moleculares de los tumores odontogénicos benignos: revisión de la literatura en el contexto de la última clasificación de la Organización Mundial de la Salud. Odontoestomatología, 24(39). https://doi.org/10.22592/ode2022n39e315
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