Keywords
Human Papillomavirus, HPV, chronic actinic cheilitis
How to Cite
Aspectos clínicos e histológicos en la queilitis actínica crónica, su relación con el Virus del Papiloma Humano. (2019). Odontoestomatología, 13(17), 45-53. https://odon.edu.uy/ojs/index.php/ode/article/view/154
Abstract
Human papilloma viruses (HPVs) are important oncogenic agents in the etiology of gynecologic cancer and now have been linked to some pre-malignant lesions and some types of oral cancers. In order to assess the presence of HPV in the cheilitis were used for the study 29 patients with and 29 patients in the control group. PCR was used to detect the presence of HPV in samples of fresh tissue from diseased lips. The chronic actinic cheilitis occurred in caucasians, 19 males and 10 females, mean age 56 years. In the analysis of the clinical features were recorded many alterations. We also evaluated the histologic features of the chronic actinic cheilitis and atypia were found in varying degrees in all cases. We conclude that all cases had negative results for viral isolation.
References
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Huber MA, Terezhalmy GT. Th e pacient with actinic cheilosis. Gen Dent 2006;54(4):274-82.
Savage NW, Mckay C, Faulkner C. Actinic Cheilitis in dental practice. Aust Dent J; Jun 2010 1, (1): 78-84.
Cavalcante AS, Anbinder AL; Carvalho YR. Actinic Cheilitis: clinical and histological fectures. J Oral Maxillofac Surg Mar 2008; 66(3): 488-503.
Czerninski R; Zini A; Sgan-Cohen HD. Lip cancer: incidence, trends, histology and survival: 1970-2006. Br J Dermatol; 2010 May 162(5):1103-9.
Mitsuishi T, Ohara K, Kawashima M, Kobayashi S, Kawana S. Prevalence of human papillomavirus DNA sequences in verrucous carcinoma of the lip: genomic and therapeutic approoaches. Cancer Lett. 2005; 26; 222(2):139-43.
Silva CEXSR, Silva IDCG, Cerri A, Weckx LL. Prevalence of human papillomavirus in squamous cell carcinoma of tongue.Oral Medicine, Oral Pathology, Oral Radiology and Endodontics. October 2007; 104(4): 497-500
Lin K, Roosinovich E, Ma B, CF Hug, TC Wu. Therapeutic HPV DNA vaccines. Immunol Res 2010; 47(1-3):86-112,
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Miller CS, Johnstone BM. Human papillomavirus as a risk factor for oral squamous cell carcinoma: A meta-analysis 1982-1997. Oral surg oral med oral pathol oral radiol endod, 2001 91(6), 622-35
Jimenez C, Correnti M, Salma N, Cavazza ME, Perrone M. Detection of human papillomavirus DNA in benign oral squamous epthelial lesions in Venezuela.J Oral Pathol Med 2001;30(7)385-8.
Summersgill KF, Smith EM, Kirchner HL, Haugen TH, Turek LP. P 53 polymorphism, human papillomavirus infection in the oral cavity and oral cancer. Oral surg oral med oral pathol oral radiol endod, 2000;90(3) 334-9.
Ibieta BR, Lizano M, Frans-Mendivil M, Barrera JL, Carrillo A, Ma Ruz-Godoy L, Mohar A. Human papillomavirus in oral squamous cell carcinoma in a Mexican population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99. 2005;(3):311-5.
Makoto K, Favre M, Obalek S, Jablonska S. Orth G. Premalignant lesions and câncer of the skin in the general population: evaluation of the role of human papillomavirusesJ Invest Dermatol 1990; 95(5):537-42.
Ostwald C, Rutsatz K, Scheweder J, Schmidt W, Gundlach K, Barten M. Human papillomavirus 6 / 11, 16 and 18 in oral carcinomas and benign oral lesions. Med Microbiol Immunol (Berl). 2003;192(3):145-8.
Van Der Waal, Diagnostic and therapeutic problems of oral precancerous lesions. Int. J. Oral Maxillofac. Surg. 1986;15:790-8.
Lewis BE, Pfeiffer BD, Mathog D, Celniker SE. Current Biology 2003; 13(15):587-8.
Aguiar SM. Contribuição ao estudo da queilite actínica: correlação anatomo-clínica 2006. 132f. Tes (Doutorado em Dermatologia) – Faculdade de Medicina da Universidade de São Paulo. São Paulo.
Wheeler CM. Natural history of human papillomavirus infections cytologic and histologic abnormalities and cáncer. Obstet Gynecol Clin North Am. 2008;35(4):519-36
Dunne EF, Markowitz LE.Genital human papillomavirus infection. Clin Infect Dis 2006;43(5)624-9.
Koppikar P, Villiers EM, Mulherkar R. Identification of human papillomaviruses in tumors of the oral cavity in an Indian community. Int J Cancer 2005;113(6):946-50.
Huber MA, Terezhalmy GT. Th e pacient with actinic cheilosis. Gen Dent 2006;54(4):274-82.
Savage NW, Mckay C, Faulkner C. Actinic Cheilitis in dental practice. Aust Dent J; Jun 2010 1, (1): 78-84.
Cavalcante AS, Anbinder AL; Carvalho YR. Actinic Cheilitis: clinical and histological fectures. J Oral Maxillofac Surg Mar 2008; 66(3): 488-503.
Czerninski R; Zini A; Sgan-Cohen HD. Lip cancer: incidence, trends, histology and survival: 1970-2006. Br J Dermatol; 2010 May 162(5):1103-9.
Mitsuishi T, Ohara K, Kawashima M, Kobayashi S, Kawana S. Prevalence of human papillomavirus DNA sequences in verrucous carcinoma of the lip: genomic and therapeutic approoaches. Cancer Lett. 2005; 26; 222(2):139-43.
Silva CEXSR, Silva IDCG, Cerri A, Weckx LL. Prevalence of human papillomavirus in squamous cell carcinoma of tongue.Oral Medicine, Oral Pathology, Oral Radiology and Endodontics. October 2007; 104(4): 497-500
Lin K, Roosinovich E, Ma B, CF Hug, TC Wu. Therapeutic HPV DNA vaccines. Immunol Res 2010; 47(1-3):86-112,
Nielsen H, Norrild B, Vedofte P. Human Papilomavirus in oral premalignant lesions. Eur J Cancer oral oncol. 1996;(32) 267-70.
Miller CS, Johnstone BM. Human papillomavirus as a risk factor for oral squamous cell carcinoma: A meta-analysis 1982-1997. Oral surg oral med oral pathol oral radiol endod, 2001 91(6), 622-35
Jimenez C, Correnti M, Salma N, Cavazza ME, Perrone M. Detection of human papillomavirus DNA in benign oral squamous epthelial lesions in Venezuela.J Oral Pathol Med 2001;30(7)385-8.
Summersgill KF, Smith EM, Kirchner HL, Haugen TH, Turek LP. P 53 polymorphism, human papillomavirus infection in the oral cavity and oral cancer. Oral surg oral med oral pathol oral radiol endod, 2000;90(3) 334-9.
Ibieta BR, Lizano M, Frans-Mendivil M, Barrera JL, Carrillo A, Ma Ruz-Godoy L, Mohar A. Human papillomavirus in oral squamous cell carcinoma in a Mexican population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99. 2005;(3):311-5.
Makoto K, Favre M, Obalek S, Jablonska S. Orth G. Premalignant lesions and câncer of the skin in the general population: evaluation of the role of human papillomavirusesJ Invest Dermatol 1990; 95(5):537-42.
Ostwald C, Rutsatz K, Scheweder J, Schmidt W, Gundlach K, Barten M. Human papillomavirus 6 / 11, 16 and 18 in oral carcinomas and benign oral lesions. Med Microbiol Immunol (Berl). 2003;192(3):145-8.
Van Der Waal, Diagnostic and therapeutic problems of oral precancerous lesions. Int. J. Oral Maxillofac. Surg. 1986;15:790-8.
Lewis BE, Pfeiffer BD, Mathog D, Celniker SE. Current Biology 2003; 13(15):587-8.
Aguiar SM. Contribuição ao estudo da queilite actínica: correlação anatomo-clínica 2006. 132f. Tes (Doutorado em Dermatologia) – Faculdade de Medicina da Universidade de São Paulo. São Paulo.
Wheeler CM. Natural history of human papillomavirus infections cytologic and histologic abnormalities and cáncer. Obstet Gynecol Clin North Am. 2008;35(4):519-36