Keywords
Caries removers; Collagen; Enzymatic proteolysis.
How to Cite
Proteolisis enzimática del colágeno dentinario. (2010). Odontoestomatología, 12(14), 35-44. https://odon.edu.uy/ojs/index.php/ode/article/view/216
Abstract
The present work proposes a revision of the dentin tissue's characteristics, specifically studying the collagen's structure, its formation, the bindings that stabilize the quaternary structure and the alteration of the collagen fibre by the action of microorganisms present in the carious dentin and by the components of the “caries removal agents”. Finally, a therapeutically clinic sequence for dentin caries is presented to reach the goal to provide a treatment guide based on the Minimal Intervention Philosophy.
References
Lehninger. Principles of Biochemistry. 3th. ed. Nelson AL and Cox MM. Worth Publishers 2000.
2. Garrett RH and Grisham CM. Saunders College Publishing.1998.
3. Alberts B; Bray D; Lewis J; Raff M; Roberts K; Watson JD. Molecular Biology of the Cell. 3ª ed. New York. Garland Publishing. 1994.
4. Kidd E; Fejerskov O. Dental Caries: The Disease and Its Clinical Management. 2d. edition. Wiley, John & Sons Incorporated. 2008.
5. Bjørndal L. Dentin Caries: Progression and Clinical Management. Oper. Dent. 2002; 27: 211–7.)
6. Ohgushi K; Fusayama T. Electron microscopic structure of the two layers of carious dentin. J Dent Res 1975; 54:1019-1026.
7. Thylstrup A; Qvist V. Principal enamel and dentine reactions during caries progression. In: Thylstrup A; Leach SA; Quist V (eds): Dentine and dentine Reactions in the oral cavity. Oxford: IRL Press (1987) 3-16.
8. Hall RC; Embery G. The Use of Immunohistochemistry in Understanding the Structure and Function of the Extracellular Matrix of Dental Tissues. Adv. Dent. Res. 1997; 11; 478.
9. Frencken JE; Sognpaisan Y; Phantumvanit P. y col. Atraumatic restorative technique: evaluation after one year. Dent J. London, Vol. 44, p.460-64, 1994.
10. Frencken JE, Holmgren CJ. Atraumatic Restorative Treatment for dental caries. Nijmegen: STI book; 1999: p 99.
11. Universidad de Salamanca. Disponible en: www.usal.es /~dbbm//modmol/modmol05/mm05t04.htm
12. Stryer L. Bioquímica. 2ª ed. Barcelona. Editorial Reverté SA. 1982. p. 167-82
13. Stryer L. Bioquímica. 4ª ed. Narcelona. Editorial Reverté SA. 1995. p. 227-8.
14. Candido L. C. Nova abordagem no tratamento de feridas. São Paulo: SENAC-SP; 2001. Disponível em: URL: http://www.feridologo.com.br/curpapaina.htm [2003 dez].
15. Pereira S; Silva L; Piccini D; Santos E; Bussadori S. Comparação in vitro do potencial antimicrobiano de dois materiais para remoção químico-mecânica da cárie. Braz. Oral Res. 2004; 18: 78.
16. Enzyme EC numbers. EC (Enzyme Commission) numbers assigned by IUPAC-IUBMB. Disponible en: www.genome.jp/htbin/get_htext?ECtable
17. Flindt M. Health and safety aspects of working with enzymes. Process Biochem 1979;13(8):3-7.
18. Flindt M. Allergy to a-amylase and papain. Lancet 1979;1:430-432. Apud: Velasco MVR. Desenvolvimento e padronização do gel contendo papaína para uso tópico. [Dissertação de Mestrado]. São Paulo: Faculdade de Ciências Farmacêuticas da USP; 1993.
19. Silva L R; Tonolli G; Santos E M; Bussadori S K. Avaliação da biocompatibilidade "in vitro" de um novo biomaterial para a remoção química e mecânica da cárie. In: 20ª Reunião Anual SBPqO, 2003, Águas de Lindóia. 2003. Anais. Pesquisa Odontológica Brasileira. v.17. p.93.
20. Lopes M; Mascarini R; Silva B; Flório F; Basting R. Effect of a papain-based gel for chemomechanical caries removal on dentin shear bond strength. J Dent Child. 2007;74(2): 93-7.
21. Corrêa FN, Rocha Rde O, Rodrigues Filho LE, Muench A, Rodrigues CR. Chemical versus conventional caries removal techniques in primary teeth: a microhardness study. J Clin Pediatr Dent. 2007;31(3):187-92.
2. Garrett RH and Grisham CM. Saunders College Publishing.1998.
3. Alberts B; Bray D; Lewis J; Raff M; Roberts K; Watson JD. Molecular Biology of the Cell. 3ª ed. New York. Garland Publishing. 1994.
4. Kidd E; Fejerskov O. Dental Caries: The Disease and Its Clinical Management. 2d. edition. Wiley, John & Sons Incorporated. 2008.
5. Bjørndal L. Dentin Caries: Progression and Clinical Management. Oper. Dent. 2002; 27: 211–7.)
6. Ohgushi K; Fusayama T. Electron microscopic structure of the two layers of carious dentin. J Dent Res 1975; 54:1019-1026.
7. Thylstrup A; Qvist V. Principal enamel and dentine reactions during caries progression. In: Thylstrup A; Leach SA; Quist V (eds): Dentine and dentine Reactions in the oral cavity. Oxford: IRL Press (1987) 3-16.
8. Hall RC; Embery G. The Use of Immunohistochemistry in Understanding the Structure and Function of the Extracellular Matrix of Dental Tissues. Adv. Dent. Res. 1997; 11; 478.
9. Frencken JE; Sognpaisan Y; Phantumvanit P. y col. Atraumatic restorative technique: evaluation after one year. Dent J. London, Vol. 44, p.460-64, 1994.
10. Frencken JE, Holmgren CJ. Atraumatic Restorative Treatment for dental caries. Nijmegen: STI book; 1999: p 99.
11. Universidad de Salamanca. Disponible en: www.usal.es /~dbbm//modmol/modmol05/mm05t04.htm
12. Stryer L. Bioquímica. 2ª ed. Barcelona. Editorial Reverté SA. 1982. p. 167-82
13. Stryer L. Bioquímica. 4ª ed. Narcelona. Editorial Reverté SA. 1995. p. 227-8.
14. Candido L. C. Nova abordagem no tratamento de feridas. São Paulo: SENAC-SP; 2001. Disponível em: URL: http://www.feridologo.com.br/curpapaina.htm [2003 dez].
15. Pereira S; Silva L; Piccini D; Santos E; Bussadori S. Comparação in vitro do potencial antimicrobiano de dois materiais para remoção químico-mecânica da cárie. Braz. Oral Res. 2004; 18: 78.
16. Enzyme EC numbers. EC (Enzyme Commission) numbers assigned by IUPAC-IUBMB. Disponible en: www.genome.jp/htbin/get_htext?ECtable
17. Flindt M. Health and safety aspects of working with enzymes. Process Biochem 1979;13(8):3-7.
18. Flindt M. Allergy to a-amylase and papain. Lancet 1979;1:430-432. Apud: Velasco MVR. Desenvolvimento e padronização do gel contendo papaína para uso tópico. [Dissertação de Mestrado]. São Paulo: Faculdade de Ciências Farmacêuticas da USP; 1993.
19. Silva L R; Tonolli G; Santos E M; Bussadori S K. Avaliação da biocompatibilidade "in vitro" de um novo biomaterial para a remoção química e mecânica da cárie. In: 20ª Reunião Anual SBPqO, 2003, Águas de Lindóia. 2003. Anais. Pesquisa Odontológica Brasileira. v.17. p.93.
20. Lopes M; Mascarini R; Silva B; Flório F; Basting R. Effect of a papain-based gel for chemomechanical caries removal on dentin shear bond strength. J Dent Child. 2007;74(2): 93-7.
21. Corrêa FN, Rocha Rde O, Rodrigues Filho LE, Muench A, Rodrigues CR. Chemical versus conventional caries removal techniques in primary teeth: a microhardness study. J Clin Pediatr Dent. 2007;31(3):187-92.