Versions
- 2024-07-12 (2)
- 2020-12-06 (1)
Keywords
tissue engineering, stem cells, bone regeneration and growth factors.
How to Cite
Bone regeneration as an example of tissue engineering in dentistry, with emphasis on the development of scaffolds. (2020). Odontoestomatología, 22(36), 74-86. https://doi.org/10.22592/ode2020n36a9
Abstract
Tissue engineering is a multidisciplinary scientific area which has the therapeutic purpose of restoring, replacing or increasing the functional activities of organic tissues.
Objectives: The objective of this work is to review the literature on tissue engineering at the level of the bucomaxilofacial area. Methods: A bibliographic search was carried out through the portals PubMed MEDLINE, Google Scholar and LILACS, using the terms “stem cells, bone regeneration and tissue growth factors”. Results: 193 positive results were obtained, of which 24 were used for the development of this work. Discussion: Several biomaterials capable of promoting bone neoformation have been exposed, its correct manipulation, the conformation of an adequate architecture and the synergy of the various properties being essential. Conclusions: Scaffolds are the ones that offer the greatest offer for their use and the choice of each one does not depend on the material itself.
References
1. Piedra MAM, Espejo SA, Moral-Munoz JA,Campos F, Chato-Astrain J, Garcia-Garcia OD, Sanchez Porras D, Antonio Campos. An Evolutive and Scientometric Research on Tissue Engineering Reviews.Tissue Eng Part A. 2019; 26 (9-10): 569-577. doi: 10.1089/ten. TEA.2019.0247. [Epub ahead of print]
2. Espejo SA, Campos F, Piedra LM, Durand Herrera D, Moral-Munoz JA,Campos A, Piedra MAM. Global Tissue Engineering Trends: A Scientometric and Evolutive Study. Tissue Eng Part A. 2018; 24 (19-20): 1504-1517.
3. Piedra MAM, Alaminos M, Fernández Valadés Gámez R, España López A, Liceras-Liceras E, Sánchez Montesinos I, Martínez-Plaza A, Sánchez-Quevedo MC, R Fernández-Valadés, Garzón I. Development of a multilayered palate substitute in rabbits: a histochemical ex vivo and in vivo analysis. Histochem Cell Biol. 2017; 147(3): 377-388.
4. Gómez de Ferraris, Campos Muñoz. Histología, embriología e ingeniería tisular bucodental, 2019, 4ta edición, editorial Médica Panamericana. P3-36.
5. Berón MP. Historia de la teoría celular. Universidad Nacional de Mar del Plata. 2006.
6. Apablaza F. Antecedentes históricos y conceptos básicos en el estudio de las células madre: células troncales, o la madre de todas las células. Rev. Actuali. Clinic. Meds. 2017; 1(1): p6-16
7. Fernández González A, Lizana Moreno A, de Pablos Ramos M, Ruiz García A, Espinosa Ibáñez O, Fernández Porcel N, Guerrero Calvo J, Arrabal M, López-Carmona F, Arias-Santiago S.
Optimización del cultivo de queratinocitos humanos para el desarrollo de un modelo de piel artificial humana: alternativas celulares como capa alimentadora. Real Academia de Medicina y Cirugía de Andalucía Oriental; Universidad de Granada. Agosto, 2016.
8. Smalley M, Ashworth A. Stem cells and breast cancer: a field in transit. Nature Reviews Cancer. 2003. 3: p832–844.
9. Gómez de Ferraris Ma.E, Campos Muñóz A. Histología, embriología e ingeniería tisular bucodental. Tercera edición. 2009. Editorial médica Panamericana. p2-26 p381-392.
10. Redón J, Jiménes L P, Urrego P A. Células madre en odontología. Revista CES Odontología. 2011; 24 (1)
11. Aquino-Martínez R, Angelo A.P, Ventura Pujol F. Calcium-containing scaffolds induce bone regeneration by regulating mesenchymal stem cell differentiation and migration. Stem cell research & therapy. 2017; 8: 265 p. doi: 10.1186/ s13287-017-0713-08.
12. Shakya A K, Kandalam U. Three-dimensional macroporous materials for tissue engineering of craniofacial bone. Br J OralMaxillofac- Surg.2017; 55 (9): 875–891.
13. Lee CL, Hajibandeh J, Suzuki T, Fan A, Shang P, Mao JJ. Three-dimensional printed multiphase scaffolds for regeneration of periodontium complex. Tissue engineering Part A. 2014; 20 (7-8): 1342-51.
14. Thrivikraman G, Athirasala A, Twohig Ch, Kumar Boda S. Biomaterials for Craniofacial Bone Regeneration. Dent Clin North Am D. 2017; 61 (4): 835-856.
15. Habraken W, Habibovic P, Epple M, Bohner M. Calcium phosphates in biomedical applications: materials for the future. Materials Today. 2016; 19 (2): 69-87.
16. Stoppel WL, et al. Clinical applications of naturally derived biopolymer-based scaffolds for regenerative medicine. Ann Biomed Eng. 2015; 43 (3): 657–80.
17. Kang Y, Kim S, Fahrenholtz M, et al. Osteogenic and angiogenic potentials of monocultured and co-cultured human-bone-marrow-derived mesenchymal stem cells and human-umbilicalvein endothelial cells on three-dimensional porous beta-tricalcium phosphate scaffold. Acta biomaterialia. 2012; 9 (1): 4906-15.
18. Tollemar V, Collier ZJ, Mohammed MK, Lee MJ, Ameer GA 4, Russell R. Stem cells, growth factors and scaffolds in craniofacial regenerative medicine. Genes Dis. 2016; 3 (1): 56–71.
19. Walsh WR, Morberg P, Yu Y, Yang JL, Haggard W, Sheath PC, Svehla M, Bruce WJM. Response of a calcium sulfate bone graft substitute in a confined cancellous defect. Clin Orthop Relat Res. 2003; 406: 228–36.
20. Martín-Del-Campo M, Sampedro JG, Flores- Cedillo ML, Rosales-Ibañez R, Rojo L. Bone Regeneration Induced by Strontium Folate Loaded Biohybrid Scaffolds. Molecules. 2019; 24 (9): 1660. doi: 10.3390/molecules24091660
21. Habraken W, Habibovic P, Epple M, Bohner M. Calcium phosphates in biomedical applica- tions: materials for the future? Materials Today. 2016; 19 (2).
22. Zhang B, Han Z, Duan K, Mu Y, Weng J. Multilayered pore-closed PLGA microsphere delivering OGP and BMP-2 in sequential release patterns for the facilitation of BMSCs osteogenic
differentiation. J Biomed Mater Res Part A. 2018; Vol106A. p95–105. DOI: 10.1002/ jbm.a.36210
23. Shen XF, Zhang YX, Gu Y, Xu Y, Liu Y, Li B. Sequential and sustained release of SDF-1 and BMP-2 from silk fibroin-nanohydroxyapatite scaffold for the enhancement of bone regeneration.
Biomaterials. 2016; 106: 205–216.
24. Mijiritsky E, Ferroni L, Gardin Ch, Bressan E, Zanette G, Piattelli A, Zavan B. Porcine Bone Scaffolds Adsorb Growth Factors Secreted by MSCs and Improve Bone Tissue Repair. Materials
(Basel, Switzerland). 2017; 10 (9): 1054. doi: 10.3390/ma10091054
2. Espejo SA, Campos F, Piedra LM, Durand Herrera D, Moral-Munoz JA,Campos A, Piedra MAM. Global Tissue Engineering Trends: A Scientometric and Evolutive Study. Tissue Eng Part A. 2018; 24 (19-20): 1504-1517.
3. Piedra MAM, Alaminos M, Fernández Valadés Gámez R, España López A, Liceras-Liceras E, Sánchez Montesinos I, Martínez-Plaza A, Sánchez-Quevedo MC, R Fernández-Valadés, Garzón I. Development of a multilayered palate substitute in rabbits: a histochemical ex vivo and in vivo analysis. Histochem Cell Biol. 2017; 147(3): 377-388.
4. Gómez de Ferraris, Campos Muñoz. Histología, embriología e ingeniería tisular bucodental, 2019, 4ta edición, editorial Médica Panamericana. P3-36.
5. Berón MP. Historia de la teoría celular. Universidad Nacional de Mar del Plata. 2006.
6. Apablaza F. Antecedentes históricos y conceptos básicos en el estudio de las células madre: células troncales, o la madre de todas las células. Rev. Actuali. Clinic. Meds. 2017; 1(1): p6-16
7. Fernández González A, Lizana Moreno A, de Pablos Ramos M, Ruiz García A, Espinosa Ibáñez O, Fernández Porcel N, Guerrero Calvo J, Arrabal M, López-Carmona F, Arias-Santiago S.
Optimización del cultivo de queratinocitos humanos para el desarrollo de un modelo de piel artificial humana: alternativas celulares como capa alimentadora. Real Academia de Medicina y Cirugía de Andalucía Oriental; Universidad de Granada. Agosto, 2016.
8. Smalley M, Ashworth A. Stem cells and breast cancer: a field in transit. Nature Reviews Cancer. 2003. 3: p832–844.
9. Gómez de Ferraris Ma.E, Campos Muñóz A. Histología, embriología e ingeniería tisular bucodental. Tercera edición. 2009. Editorial médica Panamericana. p2-26 p381-392.
10. Redón J, Jiménes L P, Urrego P A. Células madre en odontología. Revista CES Odontología. 2011; 24 (1)
11. Aquino-Martínez R, Angelo A.P, Ventura Pujol F. Calcium-containing scaffolds induce bone regeneration by regulating mesenchymal stem cell differentiation and migration. Stem cell research & therapy. 2017; 8: 265 p. doi: 10.1186/ s13287-017-0713-08.
12. Shakya A K, Kandalam U. Three-dimensional macroporous materials for tissue engineering of craniofacial bone. Br J OralMaxillofac- Surg.2017; 55 (9): 875–891.
13. Lee CL, Hajibandeh J, Suzuki T, Fan A, Shang P, Mao JJ. Three-dimensional printed multiphase scaffolds for regeneration of periodontium complex. Tissue engineering Part A. 2014; 20 (7-8): 1342-51.
14. Thrivikraman G, Athirasala A, Twohig Ch, Kumar Boda S. Biomaterials for Craniofacial Bone Regeneration. Dent Clin North Am D. 2017; 61 (4): 835-856.
15. Habraken W, Habibovic P, Epple M, Bohner M. Calcium phosphates in biomedical applications: materials for the future. Materials Today. 2016; 19 (2): 69-87.
16. Stoppel WL, et al. Clinical applications of naturally derived biopolymer-based scaffolds for regenerative medicine. Ann Biomed Eng. 2015; 43 (3): 657–80.
17. Kang Y, Kim S, Fahrenholtz M, et al. Osteogenic and angiogenic potentials of monocultured and co-cultured human-bone-marrow-derived mesenchymal stem cells and human-umbilicalvein endothelial cells on three-dimensional porous beta-tricalcium phosphate scaffold. Acta biomaterialia. 2012; 9 (1): 4906-15.
18. Tollemar V, Collier ZJ, Mohammed MK, Lee MJ, Ameer GA 4, Russell R. Stem cells, growth factors and scaffolds in craniofacial regenerative medicine. Genes Dis. 2016; 3 (1): 56–71.
19. Walsh WR, Morberg P, Yu Y, Yang JL, Haggard W, Sheath PC, Svehla M, Bruce WJM. Response of a calcium sulfate bone graft substitute in a confined cancellous defect. Clin Orthop Relat Res. 2003; 406: 228–36.
20. Martín-Del-Campo M, Sampedro JG, Flores- Cedillo ML, Rosales-Ibañez R, Rojo L. Bone Regeneration Induced by Strontium Folate Loaded Biohybrid Scaffolds. Molecules. 2019; 24 (9): 1660. doi: 10.3390/molecules24091660
21. Habraken W, Habibovic P, Epple M, Bohner M. Calcium phosphates in biomedical applica- tions: materials for the future? Materials Today. 2016; 19 (2).
22. Zhang B, Han Z, Duan K, Mu Y, Weng J. Multilayered pore-closed PLGA microsphere delivering OGP and BMP-2 in sequential release patterns for the facilitation of BMSCs osteogenic
differentiation. J Biomed Mater Res Part A. 2018; Vol106A. p95–105. DOI: 10.1002/ jbm.a.36210
23. Shen XF, Zhang YX, Gu Y, Xu Y, Liu Y, Li B. Sequential and sustained release of SDF-1 and BMP-2 from silk fibroin-nanohydroxyapatite scaffold for the enhancement of bone regeneration.
Biomaterials. 2016; 106: 205–216.
24. Mijiritsky E, Ferroni L, Gardin Ch, Bressan E, Zanette G, Piattelli A, Zavan B. Porcine Bone Scaffolds Adsorb Growth Factors Secreted by MSCs and Improve Bone Tissue Repair. Materials
(Basel, Switzerland). 2017; 10 (9): 1054. doi: 10.3390/ma10091054