Keywords
radiotherapy
dental caries
head and neck cancer
dental caries
head and neck cancer
How to Cite
Radiation-related caries treatment: a literature review. (2022). Odontoestomatología, 24(39), 1-9. https://doi.org/10.22592/ode2022n39e310
Abstract
Radiation-related caries is a frequent late complication caused by the direct and indirect effects of head and neck cancer radiotherapy. The aim of this study was to review and analyze literature on the management of radiation-related caries, restorative materials, treatment failures, and treatment protocols. A narrative search of the Pubmed, Lilacs and Web Of Science databases was performed by three independent reviewers, and inclusion and exclusion criteria were used for paper selection. According to Clinical studies and literature reviews the most used materials are conventional glass ionomer cement, resin modified glass ionomer cement and composite resin with fluoride applications. More studies are needed to define the best treatment that includes cavity preparation technique and restorative material with better results. It is recommended to carry out studies comparing different adhesive systems, fluoride concentrations and root dentin restorations.
References
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5. Moore C, Conor McListera C, Cardwell C, O'Neill C, Donnelly M, Gerald McKenna. Dental caries following radiotherapy for head and neck cancer: A systematic review. Oral Oncology. 2020; 104484. https://doi.org/10.1016/j.oraloncology.2019.104484
6. Lieshout HF, Bots CP. The effect of radiotherapy on dental hard tissue—a systematic review. Clin Oral Investig. 2014; 18(1):17–24. https://doi.org/10.1007/s00784-013-1034-z
7. Qing P, Huang S, Gao S, Qian L, Yu H. Effect of gamma irradiation on the wear behaviour of human tooth enamel. Scientific reports. 2015 5:11568. doi:10.1038/srep11568
8. Jansma J, Vissink A, Gravenmade EJ, Visch LL, Fidler V, Retief DH. In vivo study on the prevention of postradiation caries. Caries Res. 1989;23(3):172-8. https://doi.org/10.1159/000261173
9. Walker MP, Wichman B, Cheng AL, Coster J, Williams KB. Impact of Radiotherapy Dose on Dentition Breakdown in Head and Neck Cancer Patients. Practical radiation oncology. 2011;1(3):142-8. doi: 10.1016/j.prro.2011.03.003.
10. Abdalla R, Omar A, Eid K. Detecting demineralization of enamel and cementum after gamma irradiation using radiographic densitometry. Radiation and environmental biophysics. 2018;57(3):293-9. doi: 10.1007/s00411-018-0749-2. PubMed PMID: 29948141
11. Velo MMAC, Farha ALH, Santos SSP, Shiota A, Sansavino SZ, Souza AT, Honório HM, Wang L. Radiotherapy alters the composition, structural and mechanical properties of root dentin in vitro. Clinical Oral Investigations 2018. https://doi.org/10.1007/s00784-018-2373-6
12. Naves LZ, Novais VR, Armstrong SR, Correr-Sobrinho L, Soares CJ. Effect of gamma radiation on bonding to human enamel and dentin. Support Care Cancer. 2012 20:2873–2878. DOI 10.1007/s00520-012-1414-y
13. Rodrigues RB, Soares CJ, Junior PCS, Lara VC, Arana-Chavez VE, Novais VR. Influence of radiotherapy on the dentin properties and bond strength. Clin Oral Investig. 2017. doi: 10.1007/s00784-017-2165-4.
14. Wood RE, Maxymiw WG, McComb D. A clinical comparison of glass ionomer (polyalkenoate) and silver amalgam restorations in the treatment of Class 5 caries in xerostomic head and neck cancer patients. Operative Dentistry. 1993;18(3):94-102.
15. McComb D, Erickson RL, Maxymiw WG & Wood RE. A Clinical Comparison of Glass Ionomer, Resin-Modified Glass Ionomer and Resin Composite Restorations in the Treatment of Cervical Caries in Xerostomic Head and Neck Radiation Patients. Operative Dentistry, 2002; 27, 430-437.
16. Haveman CW, Summitt JB, Burgess JO, Carlson K. Three restorative materials and topical fluoride gel used in xerostomic patients: a clinical comparison. J Am Dent Assoc. 2003;134(2):177-84. doi: 10.14219/jada.archive.2003.0131.
17. Hu JY, Li YQ, Smales RJ, Yip KHK. Restoration of teeth with moreviscous glass ionomer cements following radiation-induced caries. International Dental Journal. 2002; 52, 445-448.
18. Hu JY, Chen XC, Li YQ, Smales RJ, Yip KH. Radiation-induced root surface caries restored with glass-ionomer cement placed in conventional and ART cavity preparations: results at two years. Aust Dent J. 2005;50(3):186-90. doi: 10.1111/j.1834-7819. 2005.tb00359. x.
19. De Moor RJG, Stassen IG, Veldt YV, Torbeyns D, Hommez GMG. Two-year clinical performance of glass ionomer and resin composite restorations in xerostomic head- and neck-irradiated cancer patients. Clin Oral Invest. 2011;15:31–38 DOI 10.1007/s00784-009-0355-4
20. Gupta N, Pal M, Rawat S, Mandeep S Grewal MS, Garg H, Chauhan D, Ahlawat P, et al. Radiation-induced dental caries, prevention and treatment - A systematic review. Natl J Maxillofac Surg. Jul-Dec 2015;6(2):160-6. doi: 10.4103/0975-5950.183870.
21. Palmier NR, Migliorati CA, Prado-Ribeiro AC Querido de Oliveira MC, Vechiato Filho AJV, et al. Radiation-related caries: current diagnostic, prognostic, and management paradigms. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020;130(1):52-62. doi: 10.1016/j.oooo.2020.04.003.
22. Palmier NR, Troconis CCM, Normando AGC, Guerra ENS, Araújo ALD, Arboleda LPA, Fonsêca JM, Paglioni MP, Gomes-Silva W, Vechiato Filho AJ, González-Arriagada WA, Leme AFP, Prado-Ribeiro AC, Brandão TB, Goes MF, Lopes MJ, Santos-Silva AR. Impact of head and neck radiotherapy on the longevity of dental adhesive restorations: A systematic review and meta-analysis. J Prosthet Dent. 2021;11;S0022-3913(21)00068-8.
23. Franzel W, Gerlach R, Hein HJ, Schaller HG. Effect of tumor therapeutic irradiation on the mechanical properties of teeth tissue. Z Med Phys. 2006;16(2):148-54. https://doi.org/10.1078/0939-3889-00307
2. Jham BC, da Silva Freire AR. Oral complications of radiotherapy in the head and neck. Braz J Otorhinolaryngol. 2006;72(5):704-8. https://doi.org/10.1016/S1808- 8694(15)31029-6
3. Kielbassa AM, Hinkelbein W, Hellwig E, Meyer-Luckel H. Radiation-related damage to dentition. The Lancet Oncology. 2006;7(4):326-35. doi: 10.1016/S1470-2045(06)70658-1. PubMed PMID: 16574548
4. Jawad H, Hodson NA, Nixon PJ. A review of dental treatment of head and neck cancer patients, before, during and after radiotherapy: part 1. Br Dent J. 2015;218(2):65-8. https://doi.org/10.1038/sj.bdj.2015.28
5. Moore C, Conor McListera C, Cardwell C, O'Neill C, Donnelly M, Gerald McKenna. Dental caries following radiotherapy for head and neck cancer: A systematic review. Oral Oncology. 2020; 104484. https://doi.org/10.1016/j.oraloncology.2019.104484
6. Lieshout HF, Bots CP. The effect of radiotherapy on dental hard tissue—a systematic review. Clin Oral Investig. 2014; 18(1):17–24. https://doi.org/10.1007/s00784-013-1034-z
7. Qing P, Huang S, Gao S, Qian L, Yu H. Effect of gamma irradiation on the wear behaviour of human tooth enamel. Scientific reports. 2015 5:11568. doi:10.1038/srep11568
8. Jansma J, Vissink A, Gravenmade EJ, Visch LL, Fidler V, Retief DH. In vivo study on the prevention of postradiation caries. Caries Res. 1989;23(3):172-8. https://doi.org/10.1159/000261173
9. Walker MP, Wichman B, Cheng AL, Coster J, Williams KB. Impact of Radiotherapy Dose on Dentition Breakdown in Head and Neck Cancer Patients. Practical radiation oncology. 2011;1(3):142-8. doi: 10.1016/j.prro.2011.03.003.
10. Abdalla R, Omar A, Eid K. Detecting demineralization of enamel and cementum after gamma irradiation using radiographic densitometry. Radiation and environmental biophysics. 2018;57(3):293-9. doi: 10.1007/s00411-018-0749-2. PubMed PMID: 29948141
11. Velo MMAC, Farha ALH, Santos SSP, Shiota A, Sansavino SZ, Souza AT, Honório HM, Wang L. Radiotherapy alters the composition, structural and mechanical properties of root dentin in vitro. Clinical Oral Investigations 2018. https://doi.org/10.1007/s00784-018-2373-6
12. Naves LZ, Novais VR, Armstrong SR, Correr-Sobrinho L, Soares CJ. Effect of gamma radiation on bonding to human enamel and dentin. Support Care Cancer. 2012 20:2873–2878. DOI 10.1007/s00520-012-1414-y
13. Rodrigues RB, Soares CJ, Junior PCS, Lara VC, Arana-Chavez VE, Novais VR. Influence of radiotherapy on the dentin properties and bond strength. Clin Oral Investig. 2017. doi: 10.1007/s00784-017-2165-4.
14. Wood RE, Maxymiw WG, McComb D. A clinical comparison of glass ionomer (polyalkenoate) and silver amalgam restorations in the treatment of Class 5 caries in xerostomic head and neck cancer patients. Operative Dentistry. 1993;18(3):94-102.
15. McComb D, Erickson RL, Maxymiw WG & Wood RE. A Clinical Comparison of Glass Ionomer, Resin-Modified Glass Ionomer and Resin Composite Restorations in the Treatment of Cervical Caries in Xerostomic Head and Neck Radiation Patients. Operative Dentistry, 2002; 27, 430-437.
16. Haveman CW, Summitt JB, Burgess JO, Carlson K. Three restorative materials and topical fluoride gel used in xerostomic patients: a clinical comparison. J Am Dent Assoc. 2003;134(2):177-84. doi: 10.14219/jada.archive.2003.0131.
17. Hu JY, Li YQ, Smales RJ, Yip KHK. Restoration of teeth with moreviscous glass ionomer cements following radiation-induced caries. International Dental Journal. 2002; 52, 445-448.
18. Hu JY, Chen XC, Li YQ, Smales RJ, Yip KH. Radiation-induced root surface caries restored with glass-ionomer cement placed in conventional and ART cavity preparations: results at two years. Aust Dent J. 2005;50(3):186-90. doi: 10.1111/j.1834-7819. 2005.tb00359. x.
19. De Moor RJG, Stassen IG, Veldt YV, Torbeyns D, Hommez GMG. Two-year clinical performance of glass ionomer and resin composite restorations in xerostomic head- and neck-irradiated cancer patients. Clin Oral Invest. 2011;15:31–38 DOI 10.1007/s00784-009-0355-4
20. Gupta N, Pal M, Rawat S, Mandeep S Grewal MS, Garg H, Chauhan D, Ahlawat P, et al. Radiation-induced dental caries, prevention and treatment - A systematic review. Natl J Maxillofac Surg. Jul-Dec 2015;6(2):160-6. doi: 10.4103/0975-5950.183870.
21. Palmier NR, Migliorati CA, Prado-Ribeiro AC Querido de Oliveira MC, Vechiato Filho AJV, et al. Radiation-related caries: current diagnostic, prognostic, and management paradigms. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020;130(1):52-62. doi: 10.1016/j.oooo.2020.04.003.
22. Palmier NR, Troconis CCM, Normando AGC, Guerra ENS, Araújo ALD, Arboleda LPA, Fonsêca JM, Paglioni MP, Gomes-Silva W, Vechiato Filho AJ, González-Arriagada WA, Leme AFP, Prado-Ribeiro AC, Brandão TB, Goes MF, Lopes MJ, Santos-Silva AR. Impact of head and neck radiotherapy on the longevity of dental adhesive restorations: A systematic review and meta-analysis. J Prosthet Dent. 2021;11;S0022-3913(21)00068-8.
23. Franzel W, Gerlach R, Hein HJ, Schaller HG. Effect of tumor therapeutic irradiation on the mechanical properties of teeth tissue. Z Med Phys. 2006;16(2):148-54. https://doi.org/10.1078/0939-3889-00307