Keywords
propolis
properties
uses
dentistry
properties
uses
dentistry
How to Cite
Properties and uses of propolis in dentistry: a review. (2022). Odontoestomatología, 24(40), 1-13. https://doi.org/10.22592/ode2022n40e321
Abstract
Propolis is a dark-colored sticky material obtained from various plants and mixed with wax, derived from bees who use it to protect their hives. The aim of the present work was to carry out a literature review on the properties and uses of propolis in dentistry. A bibliographic search of reports published from March 2010 to March 2020 was performed in PubMed, Imbiomed, Medigraphic, SciELO and Google Scholar using the words: propolis, properties, uses. Thirty-nine articles were selected for review. The main properties reported were: antimicrobial, anti-inflammatory, immunomodulatory, and wound healing. The main reported uses covered the following areas of dentistry: caries prevention, endodontics, periodontics, prosthodontics and surgery. In recent years, special attention has been given to the applications of propolis as its efficacy has been demonstrated in different areas of dentistry.
References
1.Felitti R. Propóleo en Odontología. Usos y aplicaciones. Act. Odontol. 2014; 11(1): 30-37.
2.Angulo M, Colina M, Contreras M, Rangel J. Efectividad de productos naturales como tratamiento de enfermedades periodontales. Rev. Venez. Invest. Odont. 2017; 5(1): 105-118.
3.Airen B, Airen-Sarkar P, Tomar U, Arya-Bishen K. Antibacterial Effect of Propolis Derived from Tribal Region on Streptococcus mutans and Lactobacillus acidophilus: An in vitro Study. J. Indio. Soc. Pedod. Prev. Dent. 2018; 36(1): 48-52.
4.Cayo-Rojas CF, Cervantes-Ganoza LA. La actividad antibacteriana de Camellia sinensis comparada con propóleo frente al Streptococcus mutans. Rev. Cub. Estomatol. 2020;57(1):29-37.
5.Bustamante ME, Belkis Q. Efectividad del propóleo en tratamientos pulpares de pulpotomía y pulpectomía. revisión sistemática. Act. Bioclínica. 2017; 7(13): 1-24.
6.Liberio SA, Pereira AL, Araújo JM, Dutra RP, Nascimiento FRF, Monteiro-Neto V, Ribeiro SMN, Goncalves AG, Guerra RNM. The Potential Use of Propolis as a Cariostatic Agent and Its Actions on Mutans Group Streptococci. J. Ethnopharmacol. 2019; 125(1): 1-9.
7.Pomilio AB. Investigación en Química de Productos Naturales en Argentina: Vinculación con la Bioquímica. Act. Bioquím. Clín. Latinoam. 2012; 46(1): 73-82.
8.Suarez-Quinodoz MA, Resende RO, Fiten de Tarallo SB. Propiedades del Propóleo y su relación con la salud y la práctica odontológica. Rev. Fac. Odontol. 2012; 7(1): 1-6.
9.Premoli G, Laguado P, Díaz N, Romero C, Villarreal J. Uso del propóleo en odontología. Act. Odontol. Venez. 2010; 48 (2): 1-13.
10.Khurshid Z, Naseem M, Zafar MS, Najeeb S, Zohaib S. Propolis: A natural biomaterial for dental and oral healthcare. J. Dent. Res. Dent. Clin. Dent. Prospects. 2017; 11(4): 265-274.
11.Parolia A, Thomas MS. Kundabala M, Mohan M. Propolis and its potential uses in oral health. Int. J. Med. Sci. 2010; 2:210-215.
12.Ishtiaq-Anjum S, Ullah A, Ali-Khan K, Attaullah M, Khan H, Muhammad-Amjad BHA, Thair M, Javed-Ansar M, Gharamh HA, Adgaba N, Kanta- Dash C. Composition and Functional Properties of Propolis (Bee Glue): A Review. Saudi. J. Biol. Sci. 2019; 26(7): 1695-1703.
13.Mayta-Tovalino F, Sacsaquispe-Contreras S, Carelli-Calle J, Alania-Mallqui J. Propóleo Peruano: Una nueva alternativa terapéutica antimicrobiana en Estomatología. Rev. Estomatol. Herediana. 2012; 22(1): 50-58.
14.Wagh VD. Propolis: A wonder bees’ product and its pharmacological potentials. Adv. Pharmacol. Sci. 2014: 1-12.
15.Amir Jalal Abbasi, Farnoush Mohammadi, Mohamad Bayat, Shimelis Megersa Gema, Hannaneh Ghadirian, et al. Applications of Propolis in Dentistry: A Review. Ethiop. J. Health. Sci. 2018; 28(4): 505-512.
16.Navarro-López JSA, Lezcano MR, Mandri MN, Gili MA, Zamudio ME. Utilización del propóleos en odontología. RAAO. 2016; 15(2): 1-4.
17.Gómez-Estrada HA, Gonzáles-Ruiz KN, Domingo-Mediana J. Medina. Actividad Antiinflamatoria de Productos Naturales. BLACPMA 2011; 10(3): 182-217.
18.Kuropatnicki AK, Szliszka E, & Krol W. Historical Aspects of Propolis Research in Modern Times. Evidence Based Alternative Med. 2013; 1-11.
19.Al-Fahdawi IH. Potential Indication of Propolis in Treatment of Oral Infection for Denture Wearers. JDODT. 2015; 3(2): 1-3.
20.Nazeri R, Ghaiour M, Abbasi S. Evaluation of Antibacterial Effect of Propolis and Its Application in Mouthwash Production. Front Dent 2019; 16(1): 1-12.
21.Eralp-Akca A, Akca G, Toksoy-Topçu F, Macit E, Pikdöken L, Özgen LS. The Comparative Evaluation of the Antimicrobial Effect of Propolis with Chlorexidine Against Oral Pathogens: An In Vitro Study. Biomed Res Int 2016; 2016: 3627463.
22.Santiago KB, Piana GM, Conti BJ, Cardoso EO, Zanutto MR, Mores Rall M, Fernandes AJr, Sforcin JM. Microbiological Control and Antibacterial Action of a Propolis-Containing Mouthwash and Control of Dental Plaque in Humans. Nat Prod Res 2018; 32(12): 1441-1445.
23.Halboub E, AL Maweri SA, AL- Wesabi M, Al-Kamel A, Shamala A, Al-Sharani A, Koppolu P. Efficacy of propolis-based mouthwashes on dental plaque and gingival inflammation: a systematic review. BMC Oral Health 2020; 20(1): 198.
24.Shabbir J, Qazi F, Farooqui W, Ahmed S, Zehra T, Khurshid Z. Effect of Chinese Propolis as an Intracanal Medicament on Post-Operative Endodontic Pain: A Double-Blind Randomized Controlled Trial. Int J Environ Res Public Health 2020; 17(2): 445-449.
25.Kayaoglu G, Ömürlü H, Akca G, Gürel M, Gençay O, Sorkun K, Salih B. Antibacterial Activity of Propolis versus Conventional Endodontic Disinfectants against Enterococcus faecalis in Infected Dentinal Tubules. J Endod 2011; 37(3): 376-381.
26.Vieira-Ozorio JE, De Oliveira-E Silva CLF , De Oliveira DA, De Sousa-Neto MD , Da Cruz-Pérez DE. Standardized Propolis Extract and Calcium Hydroxide as Pulpotomy Agents in Primary Pig Teeth. J Dent Child 2012; 79(2): 53-58.
27.Madhana-Madhubala M, Srinivasan N, Ahamed S. Comparative Evaluation of Propolis and Triantibiotic Mixture as an Intracanal Medicament Against Enterococcus Faecalis. J Endod 2011; 37(9): 1287-1289.
28.Shrivastava R, Rai VK, Kumar A, Sinha S, Tripathi P, Gupta K, Sabharwal S. An in Vitro Comparison of Endodontic Medicaments Propolis and Calcium Hydroxide Alone and in Combination with Ciprofloxacin and Moxifloxacin Against Enterococcus Faecalis. J Contemp Dent Pract 2015; 16(5): 394-399.
29.Skoskiewicz-Malinowska K, Kaczmarek U, Malicka B, Walczak K, Zietek M. Application of chitosan and propolis in endodontic treatment: a review. Mini Rev Med Chem. 2017;17(5):410-34.
30.Fernández-Montero JG. Uso odontológico de propóleos de origen costarricense. Odont Vital. 2016; 24: 43-52.
31.Salazar-Caicedo VE, Balseca-Ibarra MC, Martínez-Martínez AC. Uso de la tintura de propóleo al 0,12% en un paciente con enfermedad periodontal y agrandamiento gingival. Dom Cien. 2017; 3(1): 501-520.
32.Vanni R, Waldner-Tomic NM, Belibasakis GN, Attin T, Schmidlin PT, Thurnheer T. Antibacterial Efficacy of a Propolis Toothpaste and Mouthrinse Against a Supragingival Multispecies Biofilm. Oral Health Prev Dent 2015; 13(6): 531-5.
33.Leonel-Martins M, Nunes-Monteiro AS , Costa-Guimarães JE, Torres-Guimarães BC; et al. Cytotoxic and Antibacterial Effect of a Red Propolis Mouthwash, With or Without Fluoride, on the Growth of a Cariogenic Biofilm. Arch Oral Biol 2019; 107: 104512.
34.Ercan N, Olgún-Erdemir E, Yusel-Ozkan S, Karsiyaka-Hendek M. The comparative effect of propolis in two different vehicles; mouthwash and chewin-gum on plaque accumulation and gingival inflammation. Eur J Dent 2015; 9(2): 272-276.
35.Bravo-Venero AV, Díaz-García YM, Armas-González L. Tratamiento de la alveolitis dental con tintura de propóleos al 5 %. Rev Cub Farm 2012; 46(1): 7-104.
36.Ahmed-Daffalla K, Sabri-Mahmoud A. Propolis as a natural remedy: An update. J Int Oral Health. 2016; 8(5): 646-649.
37.Lopes-Rocha R, De Miranda J, Lages-Lima N, Oliveira-Ferreira F, Aparecido-Marinho S, Dornela-Verli F. Effect of topical propolis and dexamethasone on the healing of oral surgical wounds. Wound Healing Southern Africa 2012; 5(1): 25-30.
38.Herrera CL, Alvear M, Barrientos L, Montenegro G, Salazar LA. The antifungal effect of six commercial extracts of Chilean propolis on Candida spp. Cien. Inv. Agr. 2010; 37(1): 75-84.
39.De Carvalho-Furtado JH Jr, Rocha-Valadas LA, Sampaio-Mendonca KS, Oliveira-Filho RD, Uchoa-Gadelha LM, Mello-Fiallos N, Rodrigues-Neto EM, Mello-Fiallos AC, Franca-Fonteles MM. Propolis and its dental applications: a technological prospection. Recent Pat Biotechnol. 2018; 12(4): 288-296.
2.Angulo M, Colina M, Contreras M, Rangel J. Efectividad de productos naturales como tratamiento de enfermedades periodontales. Rev. Venez. Invest. Odont. 2017; 5(1): 105-118.
3.Airen B, Airen-Sarkar P, Tomar U, Arya-Bishen K. Antibacterial Effect of Propolis Derived from Tribal Region on Streptococcus mutans and Lactobacillus acidophilus: An in vitro Study. J. Indio. Soc. Pedod. Prev. Dent. 2018; 36(1): 48-52.
4.Cayo-Rojas CF, Cervantes-Ganoza LA. La actividad antibacteriana de Camellia sinensis comparada con propóleo frente al Streptococcus mutans. Rev. Cub. Estomatol. 2020;57(1):29-37.
5.Bustamante ME, Belkis Q. Efectividad del propóleo en tratamientos pulpares de pulpotomía y pulpectomía. revisión sistemática. Act. Bioclínica. 2017; 7(13): 1-24.
6.Liberio SA, Pereira AL, Araújo JM, Dutra RP, Nascimiento FRF, Monteiro-Neto V, Ribeiro SMN, Goncalves AG, Guerra RNM. The Potential Use of Propolis as a Cariostatic Agent and Its Actions on Mutans Group Streptococci. J. Ethnopharmacol. 2019; 125(1): 1-9.
7.Pomilio AB. Investigación en Química de Productos Naturales en Argentina: Vinculación con la Bioquímica. Act. Bioquím. Clín. Latinoam. 2012; 46(1): 73-82.
8.Suarez-Quinodoz MA, Resende RO, Fiten de Tarallo SB. Propiedades del Propóleo y su relación con la salud y la práctica odontológica. Rev. Fac. Odontol. 2012; 7(1): 1-6.
9.Premoli G, Laguado P, Díaz N, Romero C, Villarreal J. Uso del propóleo en odontología. Act. Odontol. Venez. 2010; 48 (2): 1-13.
10.Khurshid Z, Naseem M, Zafar MS, Najeeb S, Zohaib S. Propolis: A natural biomaterial for dental and oral healthcare. J. Dent. Res. Dent. Clin. Dent. Prospects. 2017; 11(4): 265-274.
11.Parolia A, Thomas MS. Kundabala M, Mohan M. Propolis and its potential uses in oral health. Int. J. Med. Sci. 2010; 2:210-215.
12.Ishtiaq-Anjum S, Ullah A, Ali-Khan K, Attaullah M, Khan H, Muhammad-Amjad BHA, Thair M, Javed-Ansar M, Gharamh HA, Adgaba N, Kanta- Dash C. Composition and Functional Properties of Propolis (Bee Glue): A Review. Saudi. J. Biol. Sci. 2019; 26(7): 1695-1703.
13.Mayta-Tovalino F, Sacsaquispe-Contreras S, Carelli-Calle J, Alania-Mallqui J. Propóleo Peruano: Una nueva alternativa terapéutica antimicrobiana en Estomatología. Rev. Estomatol. Herediana. 2012; 22(1): 50-58.
14.Wagh VD. Propolis: A wonder bees’ product and its pharmacological potentials. Adv. Pharmacol. Sci. 2014: 1-12.
15.Amir Jalal Abbasi, Farnoush Mohammadi, Mohamad Bayat, Shimelis Megersa Gema, Hannaneh Ghadirian, et al. Applications of Propolis in Dentistry: A Review. Ethiop. J. Health. Sci. 2018; 28(4): 505-512.
16.Navarro-López JSA, Lezcano MR, Mandri MN, Gili MA, Zamudio ME. Utilización del propóleos en odontología. RAAO. 2016; 15(2): 1-4.
17.Gómez-Estrada HA, Gonzáles-Ruiz KN, Domingo-Mediana J. Medina. Actividad Antiinflamatoria de Productos Naturales. BLACPMA 2011; 10(3): 182-217.
18.Kuropatnicki AK, Szliszka E, & Krol W. Historical Aspects of Propolis Research in Modern Times. Evidence Based Alternative Med. 2013; 1-11.
19.Al-Fahdawi IH. Potential Indication of Propolis in Treatment of Oral Infection for Denture Wearers. JDODT. 2015; 3(2): 1-3.
20.Nazeri R, Ghaiour M, Abbasi S. Evaluation of Antibacterial Effect of Propolis and Its Application in Mouthwash Production. Front Dent 2019; 16(1): 1-12.
21.Eralp-Akca A, Akca G, Toksoy-Topçu F, Macit E, Pikdöken L, Özgen LS. The Comparative Evaluation of the Antimicrobial Effect of Propolis with Chlorexidine Against Oral Pathogens: An In Vitro Study. Biomed Res Int 2016; 2016: 3627463.
22.Santiago KB, Piana GM, Conti BJ, Cardoso EO, Zanutto MR, Mores Rall M, Fernandes AJr, Sforcin JM. Microbiological Control and Antibacterial Action of a Propolis-Containing Mouthwash and Control of Dental Plaque in Humans. Nat Prod Res 2018; 32(12): 1441-1445.
23.Halboub E, AL Maweri SA, AL- Wesabi M, Al-Kamel A, Shamala A, Al-Sharani A, Koppolu P. Efficacy of propolis-based mouthwashes on dental plaque and gingival inflammation: a systematic review. BMC Oral Health 2020; 20(1): 198.
24.Shabbir J, Qazi F, Farooqui W, Ahmed S, Zehra T, Khurshid Z. Effect of Chinese Propolis as an Intracanal Medicament on Post-Operative Endodontic Pain: A Double-Blind Randomized Controlled Trial. Int J Environ Res Public Health 2020; 17(2): 445-449.
25.Kayaoglu G, Ömürlü H, Akca G, Gürel M, Gençay O, Sorkun K, Salih B. Antibacterial Activity of Propolis versus Conventional Endodontic Disinfectants against Enterococcus faecalis in Infected Dentinal Tubules. J Endod 2011; 37(3): 376-381.
26.Vieira-Ozorio JE, De Oliveira-E Silva CLF , De Oliveira DA, De Sousa-Neto MD , Da Cruz-Pérez DE. Standardized Propolis Extract and Calcium Hydroxide as Pulpotomy Agents in Primary Pig Teeth. J Dent Child 2012; 79(2): 53-58.
27.Madhana-Madhubala M, Srinivasan N, Ahamed S. Comparative Evaluation of Propolis and Triantibiotic Mixture as an Intracanal Medicament Against Enterococcus Faecalis. J Endod 2011; 37(9): 1287-1289.
28.Shrivastava R, Rai VK, Kumar A, Sinha S, Tripathi P, Gupta K, Sabharwal S. An in Vitro Comparison of Endodontic Medicaments Propolis and Calcium Hydroxide Alone and in Combination with Ciprofloxacin and Moxifloxacin Against Enterococcus Faecalis. J Contemp Dent Pract 2015; 16(5): 394-399.
29.Skoskiewicz-Malinowska K, Kaczmarek U, Malicka B, Walczak K, Zietek M. Application of chitosan and propolis in endodontic treatment: a review. Mini Rev Med Chem. 2017;17(5):410-34.
30.Fernández-Montero JG. Uso odontológico de propóleos de origen costarricense. Odont Vital. 2016; 24: 43-52.
31.Salazar-Caicedo VE, Balseca-Ibarra MC, Martínez-Martínez AC. Uso de la tintura de propóleo al 0,12% en un paciente con enfermedad periodontal y agrandamiento gingival. Dom Cien. 2017; 3(1): 501-520.
32.Vanni R, Waldner-Tomic NM, Belibasakis GN, Attin T, Schmidlin PT, Thurnheer T. Antibacterial Efficacy of a Propolis Toothpaste and Mouthrinse Against a Supragingival Multispecies Biofilm. Oral Health Prev Dent 2015; 13(6): 531-5.
33.Leonel-Martins M, Nunes-Monteiro AS , Costa-Guimarães JE, Torres-Guimarães BC; et al. Cytotoxic and Antibacterial Effect of a Red Propolis Mouthwash, With or Without Fluoride, on the Growth of a Cariogenic Biofilm. Arch Oral Biol 2019; 107: 104512.
34.Ercan N, Olgún-Erdemir E, Yusel-Ozkan S, Karsiyaka-Hendek M. The comparative effect of propolis in two different vehicles; mouthwash and chewin-gum on plaque accumulation and gingival inflammation. Eur J Dent 2015; 9(2): 272-276.
35.Bravo-Venero AV, Díaz-García YM, Armas-González L. Tratamiento de la alveolitis dental con tintura de propóleos al 5 %. Rev Cub Farm 2012; 46(1): 7-104.
36.Ahmed-Daffalla K, Sabri-Mahmoud A. Propolis as a natural remedy: An update. J Int Oral Health. 2016; 8(5): 646-649.
37.Lopes-Rocha R, De Miranda J, Lages-Lima N, Oliveira-Ferreira F, Aparecido-Marinho S, Dornela-Verli F. Effect of topical propolis and dexamethasone on the healing of oral surgical wounds. Wound Healing Southern Africa 2012; 5(1): 25-30.
38.Herrera CL, Alvear M, Barrientos L, Montenegro G, Salazar LA. The antifungal effect of six commercial extracts of Chilean propolis on Candida spp. Cien. Inv. Agr. 2010; 37(1): 75-84.
39.De Carvalho-Furtado JH Jr, Rocha-Valadas LA, Sampaio-Mendonca KS, Oliveira-Filho RD, Uchoa-Gadelha LM, Mello-Fiallos N, Rodrigues-Neto EM, Mello-Fiallos AC, Franca-Fonteles MM. Propolis and its dental applications: a technological prospection. Recent Pat Biotechnol. 2018; 12(4): 288-296.