Keywords
mycosis
Invasive Fungal Infections
Pathological Conditions
Signs and Symptoms
mycobiome
How to Cite
Abstract
Introduction:Paracoccidioidomycosis is an endemic mycosis in different Latin American countries, including areas of Colombia, with a very varied clinical manifestation since it is considered a disease that can be chronic and systemic. Objectives: To expose the importance of the clinical-stomatological examination in the detection of different entities in the stomatognathic system, and
the multidisciplinary management of oral and systemic paracoccidioidomycosis. Clinical case:male patient in the sixth decade
of life, who presented glossalgia and pain in the ocular region. Clinically, it presents a granulomatous-type lesion on the lateral
edges of the tongue with evolution of approximately 1 year ago, the result of the biopsy is paracoccidioidomycosis, multidisciplinary management is started with intravenous and oral medications, after 10 months it resolves. Conclusions:a good questioning, analysis of the clinical picture and complementary tests are key to early diagnosis and timely treatment, preserving the patient’s life, especially in opportunistic infections such as paracoccidioidomycosis.
References
Mutalik VS, Bissonnette C, Kalmar JR, McNamara KK. Unique Oral Presentations of Deep Fungal Infections: A Report of Four Cases. Head Neck Pathol. 2021;15(2):682-690. Doi:https://doi.org/10.1007/s12105-020-01217-0.
Drummond-Suinaga T., Gomez G., Blanco-Arandia P. Paracoccidioidomicosis juvenil diseminada y tuberculosis miliar: Reporte de un caso. Rev Panam Enf Inf. 2022; 5(1):e2. Disponible en: https://ojs2.utp.edu.co/index.php/panamericana/article/view/25086/16745.
Santos LA, Grisolia JC, Burger E, de Araujo Paula FB, Dias ALT, Malaquias LCC. Virulence factors of Paracoccidioides brasiliensis as therapeutic targets: a review. Antonie Van Leeuwenhoek. 2020;113(5):593-604. Doi: https://doi.org/10.1007/s10482-019-01382-5.
Ashraf N, Kubat RC, Poplin V, Adenis AA, Denning DW, Wright L, McCotter O, Schwartz IS, Jackson BR, Chiller T, Bahr NC. Re-drawing the Maps for Endemic Mycoses. Mycopathologia. 2020;185(5):843-865. Doi: https://doi.org/10.1007/s11046-020-00431-2.
Alvarado P, Teixeira MM, Cavallera E, Paes HC, Guerra G, Santander G, Merino-Alado R. Epidemiology of paracoccidioidomycosis in Venezuela: a retrospective study from 1954 to 2019. Mem Inst Oswaldo Cruz. 2021;8116:e210203. Doi: https://doi.org/10.1590/0074-02760210203.
Ramirez S., Ayala-Castillo Ml. Paracoccidioidomicosis con compromiso de sistema nervioso central. Acta Neurol Colomb. 2021;37(1Suppl 1): 106-111. Doi: https://doi.org/10.22379/24224022341.
Garropoli, Gastón J; Silva Balbuena, Micaela S; Cabrero, María del Carmen. Paracoccidioidomicosis: Reporte de un caso clínico con repercusión oral. Rev. Soc. Odontol. La Plata, 2022; XXXII(62):7-10. Disponible en: http://www.scielo.edu.uy/scielo.php?pid=S2393 67972019000300043&script=sci_arttext.
de Macedo PM, Teixeira MM, Barker BM, Zancopé-Oliveira RM, Almeida-Paes R, Francesconi do Valle AC. Clinical features and genetic background of the sympatric species Paracoccidioides brasiliensis and Paracoccidioides americana. PLoS Negl Trop Dis. 2019;13(4):e0007309. Doi: https://doi.org/10.1371/journal.pntd.0007309.
Tomo S, da Silva RL, Miyahara GI, Stefanini AR, Simonato LE. Diagnosis and treatment of primary paracoccidioidomycosis in oral mucosa. Dermatol Ther. 2020;33(3):e13314. Doi: https://doi.org/10.1111/dth.13314.
Wagner G, Moertl D, Glechner A, Mayr V, Klerings I, Zachariah C, Van den Nest M, Gartlehner G, Willinger B. Paracoccidioidomycosis Diagnosed in Europe-A Systematic Literature Review. J Fungi (Basel). 2021;7(2):157. Doi: https://doi.org/10.3390/jof7020157.
Ribeiro SM, Nunes TF, Cavalcante RS, Paniago AMM, Pereira BAS, Mendes RP. A scoping study of pulmonary paracoccidioidomycosis: severity classification based on radiographic and tomographic evaluation. J Venom Anim Toxins Incl Trop Dis. 2022;28:e20220053. Doi: https://doi.org/10.1590/1678-9199-jvatitd-2022-0053.
Berbeo-Velásquez Y., Vélez-López N., Vargas-Suaza, G., Ruiz-Restrepo J. Paracoccidioidomicosis crónica diseminada. Rev Asoc Colomb Dermatol.2022;30(1):60-63. Doi: https://doi.org/10.29176/2590843X.1731.
Barrios OI, Anido EV, Morera PM. Declaración de Helsinki: cambios y exégesis. Revista Cubana de Salud Pública. 2016;42(1):132-142. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=64992.
Lemus-Espinoza D, Teresa Maniscalchi MB. Micosis sistémicas en pacientes del estado Anzoátegui, Venezuela, 2009-2018. Revista de la Sociedad Venezolana de Microbiología, 2021;41:27-32. Disponible en: https://www.researchgate.net/profile/Maria Maniscalchi/publication/362452087_Micosis_sistemicas_en_pacientes_del_estado_Anzoategui_Venezuela_2009-2018/links/62ea8a374532247693780f65/Micosis-sistemicas-en-pacientes-del-estado-Anzoategui-Venezuela-2009-2018.pdf
Costa A., Dos Santos V., Leite M., de Farias F. A Brazilian male with typical oral and pulmonary paracoccidioidomycosis. Med J Islam Repub Iran. 2019; 33:145. DOI: 10.34171/mjiri.33.145.
Dutra LM, Silva THM, Falqueto A, Peçanha PM, Souza LRM, Gonçalves SS, Velloso TRG. Oral paracoccidioidomycosis in a single-center retrospective analysis from a Brazilian southeastern population. J Infect Public Health. 2018;11(4):530-533. DOI: 10.1016/j.jiph.2017.10.009.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.