Vol. 26 No. 44 (2024), Clinical cases
Vol. 26 No. 44 (2024)

Necrotizing sialometaplasia: report of a self-limitinglesion with malignant appearance

Clinical cases
Published 2024-11-27 — Updated on 2024-11-27
Caio Cesar de Souza Loureiro
Oral Medicine Service of São Sebastião Dental Specialties Center, São Sebastião, São Paulo, Brazil.
https://orcid.org/0009-0009-3063-530X
Alberi José Thomas
Oral Medicine Service of São Sebastião Dental Specialties Center, São Sebastião, São Paulo, Brazil.
https://orcid.org/0009-0000-9975-4643
Mateus José Dutra
Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (Unesp), São José dos Campos, Brazil.
https://orcid.org/0000-0002-8338-3857
Ana Lia
Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (Unesp), São José dos Campos, Brazil.
https://orcid.org/0000-0003-3930-4274

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Keywords

Necrotizing sialometaplasia
Salivary gland neoplasms
Squamous Cell Carcinoma of Head and Neck
Oral ulcer

How to Cite

Necrotizing sialometaplasia: report of a self-limitinglesion with malignant appearance. (2024). Odontoestomatología, 26(44). https://doi.org/10.22592/ode2024n44e420
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Abstract

We report a case of a 45-year-old man with a palate ulcer for 10 days. The patient was an alcohol user and had a history of using cocaine for 17 years, discontinued for the last 7 years. An incisional biopsy was performed, and histological sections revealed an extensive ulcerated area covered by a fibrinopurulent membrane, with small nests of squamous cells that presented eosinophilic cytoplasm, evident and sometimes multiple nucleoli, mild cellular atypia, and several mitotic figures. The clinical and histological characteristics indicated a Necrotizing Sialometaplasia diagnosis, and the patient
underwent clinical follow-up. In the third week of follow-up, remission of the lesion became apparent. We emphasize the importance of histopathological and immunohistochemical examination in the correct diagnosis.

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Copyright (c) 2024 Caio Cesar de Souza Loureiro, Alberi José Thomas de Souza Júnior, Mateus José Dutra, Ana Lia Anbinder

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