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Vol. 26 No. 44 (2024), Clinical cases

Vol. 26 No. 44 (2024)

Necrotizing sialometaplasia: report of a self-limitinglesion with malignant appearance

Clinical cases

Published 2024-11-27

Caio Cesar de Souza Loureiro⁺⁻
Alberi José Thomas⁺⁻
Mateus José Dutra⁺⁻
Ana Lia⁺⁻

Caio Cesar de Souza Loureiro

Oral Medicine Service of São Sebastião Dental Specialties Center, São Sebastião, São Paulo, Brazil.

https://orcid.org/0009-0009-3063-530X

Alberi José Thomas

Oral Medicine Service of São Sebastião Dental Specialties Center, São Sebastião, São Paulo, Brazil.

https://orcid.org/0009-0000-9975-4643

Mateus José Dutra

Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (Unesp), São José dos Campos, Brazil.

https://orcid.org/0000-0002-8338-3857

Ana Lia

Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (Unesp), São José dos Campos, Brazil.

https://orcid.org/0000-0003-3930-4274

Versions

2024-11-27 (2)
2024-11-27 (1)

Keywords

Necrotizing sialometaplasia
Salivary gland neoplasms
Squamous Cell Carcinoma of Head and Neck
Oral ulcer

How to Cite

Necrotizing sialometaplasia: report of a self-limitinglesion with malignant appearance. (2024). Odontoestomatología, 26(44). https://doi.org/10.22592/ode2024n44e420

Abstract

We report a case of a 45-year-old man with a palate ulcer for 10 days. The patient was an alcohol user and had a history of using cocaine for 17 years, discontinued for the last 7 years. An incisional biopsy was performed, and histological sections revealed an extensive ulcerated area covered by a fibrinopurulent membrane, with small nests of squamous cells that presented eosinophilic cytoplasm, evident and sometimes multiple nucleoli, mild cellular atypia, and several mitotic figures. The clinical and histological characteristics indicated a Necrotizing Sialometaplasia diagnosis, and the patient
underwent clinical follow-up. In the third week of follow-up, remission of the lesion became apparent. We emphasize the importance of histopathological and immunohistochemical examination in the correct diagnosis.

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