Versions
- 2026-06-23 (3)
- 2026-06-02 (2)
- 2026-05-19 (1)
Keywords
Operative
Palatal Expansion Technique
SARPE
Platelet-Rich Plasma
Fibrin
blood products
How to Cite
Abstract
In the last decades, blood derivatives have brought advances in different surgical fields. Maxillofacial surgery has not been exempt. Among the advantages of these products are the growth factors and the presence of platelets that accelerate the platelet plug formation process, which is very useful in surgeries with the probability of abundant bleeding. We present the case of a 23 year old patient, operated of Surgically Assisted Rapid Palatal Expansion (SARPE) in the Hospital Dr. Ravera Zunino of Rancagua, with direct application of the Vivostat system in nostrils, and approaches of Le Fort 1 osteotomy, verifying minimal bleeding in the intraoperative period without the need of systemic management with hypotension controlled by anesthesiology. The use of spray-on fibrin glue, the Vivostat® system, has been shown to be an effective and safe tool for reducing intraoperative and postoperative bleeding, while also offering improved surgical control and uniform sealing of the access points. The findings suggest a potential clinical benefit that requires confirmation in larger studies.
References
Carvalho PHA, Moura LB, Trento GS, Holzinger D, Gabrielli MAC, Gabrielli MFR, et al. Surgically assisted rapid maxillary expansion: a systematic review of complications. Int J Oral Maxillofac Surg. 2020 Mar;49(3):325–32.
Gogna N, Johal AS, Sharma PK. The stability of surgically assisted rapid maxillary expansion (SARME): A systematic review. J Craniomaxillofac Surg. 2020 Sep;48(9):845–52.
Cakarer S, Keskin B, Isler SC, Cansiz E, Uzun A, Keskin C. Complications associated with surgically assisted rapid palatal expansion without pterygomaxillary separation. J Stomatol Oral Maxillofac Surg. 2017 Oct;118(5):279–82.
Bortolotti F, Solidoro L, Bartolucci ML, Incerti Parenti S, Paganelli C, Alessandri-Bonetti G. Skeletal and dental effects of surgically assisted rapid palatal expansion: a systematic review of randomized controlled trials. Eur J Orthod. 2020 Sep 11;42(4):434–40.
Sygouros A, Motro M, Ugurlu F, Acar A. Surgically assisted rapid maxillary expansion: cone-beam computed tomography evaluation of different surgical techniques and their effects on the maxillary dentoskeletal complex. Am J Orthod Dentofacial Orthop. 2014 Dec;146(6):748–57.
Jędrzejewski M, Smektała T, Sporniak-Tutak K, Olszewski R. Preoperative, intraoperative, and postoperative complications in orthognathic surgery: a systematic review. Clin Oral Investig. 2015 Jun;19(5):969–77.
Tapia P, Saroza M, Arrue P, Mordoh S, Guerrero M. Uso de Sistema Vivostat® como hemoderivado sellador de abordajes en cirugía ortognática y reconstrucciones de los maxilares, reporte de 23 casos: Use of the Vivostat® system as a sealing blood product for approaches in orthognathic surgery and maxillary reconstructions, report of 23 cases. Ars Med. 2023;48(1):23–6.
Belboul A, Dernevik L, Aljassim O, Skrbic B, Rådberg G, Roberts D. The effect of autologous fibrin sealant (Vivostat) on morbidity after pulmonary lobectomy: a prospective randomized, blinded study. Eur J Cardiothorac Surg. 2004;26(6):1187–91.
Graziano F, Certo F, Basile L, Maugeri R, Grasso G, Meccio F. Autologous fibrin sealant (Vivostat®) in the neurosurgical practice: Part I: Intracranial surgical procedure. Surg Neurol Int [Internet]. 2015;6. Available from: http://dx.doi.org/10.4103/2152-7806.156871
Dodd RA, Cornwell R, Holm NE, Garbarsch A, Hollingsbee DA. The Vivostat application system: a comparison with conventional fibrin sealant application systems. Technol Health Care. 2002;10(5):401–11.
Pino A, Frattini F, Sun H, Zhang D, Wu CW, Kim HY, et al. Use of Vivostat® autologous fibrin sealant in thyroid surgery. Surg Technol Int. 2021 May 20;38:57–61.
Spotnitz WD. Fibrin sealant: The only approved hemostat, sealant, and adhesive-a laboratory and clinical perspective. ISRN Surg. 2014 Mar 4;2014:203943.
Peleg O, Mahmoud R, Shuster A, Arbel S, Manor Y, Ianculovici C, et al. Orthognathic surgery complications: The 10-year experience of a single center. J Craniomaxillofac Surg. 2021 Oct;49(10):891–7.
Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet-rich plasma: Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;85:638–46.
Simonpieri A, Del Corso M, Vervelle A, Jimbo R, Inchingolo F, Sammartino G, et al. Current knowledge and perspectives for the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in oral and maxillofacial surgery part 2: Bone graft, implant and reconstructive surgery. Curr Pharm Biotechnol. 2012 Jun;13(7):1231–56.
Miron RJ, Zucchelli G, Pikos MA, Salama M, Lee S, Guillemette V, et al. Use of platelet-rich fibrin in regenerative dentistry: a systematic review. Clin Oral Investig. 2017 Jul;21(6):1913–27.
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Copyright (c) 2026 Sofía Díaz Abarza, Pedro Tapia Contreras, Jessica Zeballos, Tomás Meza, Maria Ignacia Guerrero, Florencia Jollan, Gustavo Matus, Tomas Chesta