Palavras-chave
dentina; remineralización; biomimética.
Como Citar
Materiales bioactivos en la remineralización dentinaria. (2016). Odontoestomatología, 18(28), 11-19. https://odon.edu.uy/ojs/index.php/ode/article/view/37
Resumo
Resumen El enfoque en el tratamiento de las lesiones cariosas que afectan el tejido dentinario se ha modificado de forma dramática en las últimas décadas. El conocimiento acerca de la etiología de la caries dental, la fisiopatología dentinaria y el desarrollo de biomateriales dentales y técnicas adhesivas, han confluido en tratamientos de mínima intervención. En virtud de esta nueva alternativa en el tratamiento de las lesiones dentinarias, es necesario evaluar la posible recuperación de la dentina mediante tratamientos remineralizantes y el desarrollo de materiales bioactivos que posibiliten la reparación o regeneración del tejido imitando los mecanismos fisiológicos de mineralización y recomponiendo las propiedades mecánicas originales del tejido, con el fin de obtener resultados clínicos exitosos basados en tratamientos con enfoque biomimético.
Palabras clave : dentina; remineralización; biomimética.
Referências
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3. Kinney JH, Habelitz S, Marshall SJ, Marshall GW. The importance of intrafibrillar mineralization of collagen on the mechanical properties of dentin. J Dent Res. 2003; 82 (12) 957-61
4. Ten Cate JM. Remineralization of caries lesions extending into dentin. J Dent Res. 2001; 80 (5): 1407-11.
5. Veis A. Biomineralization: on the trail of the phosphate. Part I: Chance encounters and the path to dentin. J Dent Res. 2003; 82 (12): 941-43.
6. Bresciani E, Wagner WC, Navarro MFL, Dickens SH, Peters MC. In vivo dentin microhardness beneath a calcium phosphate cement. J Dent Res. 2010 89(8) 836- 41.
7. Mehdawi I, Abou Neel EA, Valappil SP, Palmer G, Salih V, Pratten J, Spratt DA, Young AM. Development of remineralizing, antibacterial dental materials. Acta Biomater. 2009; 5: 2525-39.
8. Smith AJ, Tobias RS, Murray PE. Transdentinal stimulation of reactionary dentinogenesis in ferrets by dentine matrix components. J Dent. 2001; 29: 341-46.
9. Bjorndal L, Reit C, Bruun G, Markvart M, Kjaldgaard M, Nasman P et al. Treatment of deep caries lesions in adults: randomized clinical trials comparing stepwise vs. direct complete excavation, and direct pulp capping vs. partial pulpotomy. Eur J Oral Sci. 2010; 118: 290-7.
10. Alves L, Fontanella V, Damo A, Ferreira de Oliveira E, Maltz M. Qualitative and quantitative radiographic assessment of sealed carious dentin: a 10-year prospective study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jan;109(1):135-41.
11. Schwendicke F. Incomplete Caries Removal : A Systematic Review and Meta-analysis. J Dent Res 2013; 92 (4): 306-14.
12. Maltz M, Oliveira EF, Fontanella V, Carminatti G. Deep caries Lesions after incomplete dentine caries removal: 40-month follow-up study. Caries Res 2007; 41(6):493-6.
13. Shibata Y, He LH, Kataoka Y, Miyazaki T, Swain MV. Micromechanical property recovery of human carious dentin achieved with colloidal nano-beta-tricalcium phosphate. J Dent Res. 2008; 87:233–7
14. Bertassoni LE, Habelitz S, Kinney JH, Marshall SJ, Marshall GW. Biomechanical perspective on the remineralization of dentin. Caries Res. 2009; 43: 70-7.
15. Hannig M, Hannig C. Nanomaterials in preventive dentistry. Nat Nanotechnol 2010; 5:565–9.
16. Gu L, Kim YK, Liu Y, Ryou H, Wimmer CE, Dai L, Arola DD, Looney SW, Pachley DH, Tay FR. Biomimetic analogs for collagen biomineralization. J Dent Res.2011; 90 (1): 82-7.
17. Yli-Urpo H, Narhi M, Narhi T. Compuond changes and tooth mineralization effects of a glass ionomer cements containing bioactive glass (S53P4), an in vivo study. Biomater. 2005; 26: 5934-41.
18. Prabhakar AR, Paul J, Besappa N. Comparative evaluation of the remineralizing effects and surface microhardness of glass ionomer cements containing bioactive glass (S53P4): an in vitro study. Int J Clin Ped Dent. 2010; 3 (2): 69-77.
19. Salonen JI, Arjasamaa M, Tuominen U, Behbehani MJ, Zaatar EI. Bioactive glass in dentistry. J Minim Interv Dent. 2009; 2(4): 208-18.
20. Tay FR, Pashley DH. Guided tissue remineralization of partially demineralized human dentin. Biomater. 2008; 29: 1127-37.
21. Skrtic D, Antonucci JM, Eanes ED. Amorphous calcium phosphate-based bioactive polymeric composites for mineralized tissue regeneration. J Res Natl Inst Stand Technol . 2003; 108: 167-82.
22. Reynolds EC. Calcium phosphate-based remineralization systems: Scientific evidence? Austr Dent J 2008; 53:268-73.
23. Dickens SH, Flaim GM, Takagi S. Mechanical properties and biochemical activity of remineralizing resin-based Ca-PO4 cements. Dent Mater.2003;19:558-66.
24. Gandolfi MG, Taddei P, Siboni F, Modena E, De Stefano ED, Prati C. Biomimetic remineralization of human dentin using promising innovative calcium silicate hybrid “smart”materials. Dent Mater. 2011. 27. 1055 69.
25. Guentsch A, Seidler K, Nietzsche S, Hefti AF, Preshaw PM, Watts DC, Jandt KD, Sigusch BW. Biomimetc mineralization: long-term observations in patients with dentin sensitivity. Dent Mater. 2012; 28: 457-64.
26. Saito T, Yamauchi M, Crenshaw MA. Apatite induction by insoluble dentin collagen. J Bone Miner Res. 1998; 13(2): 265-70.
27. Rahiotis C, Vougiouklakis G. Effect of a CPP-ACP agent on the demineralization and remineralization of dentine in vitro. J Dent. 2007; 35: 695-98.
28. Vollenweider M, Brunner TJ, Knecht S, Grass RN, Zehnder M, Imfeld T, Stark WJ. Remineralization of human dentin using ultrafine bioactive glass particles. Acta Biomater. 2007; 3: 936-43.
29. Kim YK, Yiu CKY, Kim JR, Gu L, Kim SK, Weller RN, Pashley DH, Tay FR. Failure of a glass ionomer to remineralize apatite depleted dentin. J Dent Res. 2010. 89(3) 230 35.
30. Mantri SS, Mantri SP. The nano era in dentistry. Sci Biol Med. 2013 Jan-Jun; 4(1): 39–44.
3. Kinney JH, Habelitz S, Marshall SJ, Marshall GW. The importance of intrafibrillar mineralization of collagen on the mechanical properties of dentin. J Dent Res. 2003; 82 (12) 957-61
4. Ten Cate JM. Remineralization of caries lesions extending into dentin. J Dent Res. 2001; 80 (5): 1407-11.
5. Veis A. Biomineralization: on the trail of the phosphate. Part I: Chance encounters and the path to dentin. J Dent Res. 2003; 82 (12): 941-43.
6. Bresciani E, Wagner WC, Navarro MFL, Dickens SH, Peters MC. In vivo dentin microhardness beneath a calcium phosphate cement. J Dent Res. 2010 89(8) 836- 41.
7. Mehdawi I, Abou Neel EA, Valappil SP, Palmer G, Salih V, Pratten J, Spratt DA, Young AM. Development of remineralizing, antibacterial dental materials. Acta Biomater. 2009; 5: 2525-39.
8. Smith AJ, Tobias RS, Murray PE. Transdentinal stimulation of reactionary dentinogenesis in ferrets by dentine matrix components. J Dent. 2001; 29: 341-46.
9. Bjorndal L, Reit C, Bruun G, Markvart M, Kjaldgaard M, Nasman P et al. Treatment of deep caries lesions in adults: randomized clinical trials comparing stepwise vs. direct complete excavation, and direct pulp capping vs. partial pulpotomy. Eur J Oral Sci. 2010; 118: 290-7.
10. Alves L, Fontanella V, Damo A, Ferreira de Oliveira E, Maltz M. Qualitative and quantitative radiographic assessment of sealed carious dentin: a 10-year prospective study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jan;109(1):135-41.
11. Schwendicke F. Incomplete Caries Removal : A Systematic Review and Meta-analysis. J Dent Res 2013; 92 (4): 306-14.
12. Maltz M, Oliveira EF, Fontanella V, Carminatti G. Deep caries Lesions after incomplete dentine caries removal: 40-month follow-up study. Caries Res 2007; 41(6):493-6.
13. Shibata Y, He LH, Kataoka Y, Miyazaki T, Swain MV. Micromechanical property recovery of human carious dentin achieved with colloidal nano-beta-tricalcium phosphate. J Dent Res. 2008; 87:233–7
14. Bertassoni LE, Habelitz S, Kinney JH, Marshall SJ, Marshall GW. Biomechanical perspective on the remineralization of dentin. Caries Res. 2009; 43: 70-7.
15. Hannig M, Hannig C. Nanomaterials in preventive dentistry. Nat Nanotechnol 2010; 5:565–9.
16. Gu L, Kim YK, Liu Y, Ryou H, Wimmer CE, Dai L, Arola DD, Looney SW, Pachley DH, Tay FR. Biomimetic analogs for collagen biomineralization. J Dent Res.2011; 90 (1): 82-7.
17. Yli-Urpo H, Narhi M, Narhi T. Compuond changes and tooth mineralization effects of a glass ionomer cements containing bioactive glass (S53P4), an in vivo study. Biomater. 2005; 26: 5934-41.
18. Prabhakar AR, Paul J, Besappa N. Comparative evaluation of the remineralizing effects and surface microhardness of glass ionomer cements containing bioactive glass (S53P4): an in vitro study. Int J Clin Ped Dent. 2010; 3 (2): 69-77.
19. Salonen JI, Arjasamaa M, Tuominen U, Behbehani MJ, Zaatar EI. Bioactive glass in dentistry. J Minim Interv Dent. 2009; 2(4): 208-18.
20. Tay FR, Pashley DH. Guided tissue remineralization of partially demineralized human dentin. Biomater. 2008; 29: 1127-37.
21. Skrtic D, Antonucci JM, Eanes ED. Amorphous calcium phosphate-based bioactive polymeric composites for mineralized tissue regeneration. J Res Natl Inst Stand Technol . 2003; 108: 167-82.
22. Reynolds EC. Calcium phosphate-based remineralization systems: Scientific evidence? Austr Dent J 2008; 53:268-73.
23. Dickens SH, Flaim GM, Takagi S. Mechanical properties and biochemical activity of remineralizing resin-based Ca-PO4 cements. Dent Mater.2003;19:558-66.
24. Gandolfi MG, Taddei P, Siboni F, Modena E, De Stefano ED, Prati C. Biomimetic remineralization of human dentin using promising innovative calcium silicate hybrid “smart”materials. Dent Mater. 2011. 27. 1055 69.
25. Guentsch A, Seidler K, Nietzsche S, Hefti AF, Preshaw PM, Watts DC, Jandt KD, Sigusch BW. Biomimetc mineralization: long-term observations in patients with dentin sensitivity. Dent Mater. 2012; 28: 457-64.
26. Saito T, Yamauchi M, Crenshaw MA. Apatite induction by insoluble dentin collagen. J Bone Miner Res. 1998; 13(2): 265-70.
27. Rahiotis C, Vougiouklakis G. Effect of a CPP-ACP agent on the demineralization and remineralization of dentine in vitro. J Dent. 2007; 35: 695-98.
28. Vollenweider M, Brunner TJ, Knecht S, Grass RN, Zehnder M, Imfeld T, Stark WJ. Remineralization of human dentin using ultrafine bioactive glass particles. Acta Biomater. 2007; 3: 936-43.
29. Kim YK, Yiu CKY, Kim JR, Gu L, Kim SK, Weller RN, Pashley DH, Tay FR. Failure of a glass ionomer to remineralize apatite depleted dentin. J Dent Res. 2010. 89(3) 230 35.
30. Mantri SS, Mantri SP. The nano era in dentistry. Sci Biol Med. 2013 Jan-Jun; 4(1): 39–44.