Cómo citar
Rol de los Probióticos como bacterioterapia en Odontología. Revisión de la literatura. (2019). Odontoestomatología, 19(30), 4-13. https://odon.edu.uy/ojs/index.php/ode/article/view/169
Resumen
Según la OMS/FAO probióticos son “microorganismos vivos que administrados en cantidades adecuadas conferen un benefcio para la salud del huésped.” El objetivo de este trabajo es describir el benefcio de los probióticos en la prevención de enfermedades bucales. Se realizó una búsqueda de los últimos 5 años en Web Of Science, PubMed y Scielo. Obtuvimos como resultado que los probióticos son capaces de producir antimicrobianos, competir por sitios de adhesión celular, modular el sistema inmunológico y degradar toxinas; generando en la comunidad odontológica estudios con enfoque en: reducción de la incidencia de caries, mejorar el pronóstico de periodontitis y disminución de halitosis y candidiasis. Los probióticos pueden ser un valioso complemento para la prevención de enfermedades bucales. Sin embargo, aún existen dudas sobre cuál es la mejor cepa bacteriana, dosis y momento de administración, por lo cual se requieren estudios longitudinales futuros.
Referencias
1. Kistler JO, Pesaro M & Wade W. Development and pyrosequencing analysis of an in-vitro oral bioflm model. BMC Microbiol. 2015;10:15:24 DOI: 10.1186/s12866-015-0364-1
2. Srivastava S, Sabyasachi S, Kumari M & Mohd S. Effect of Probiotic Curd on Salivary pH and Streptococcus mutans: A Double Blind Parallel Randomized Controlled Trial. J Clin Diagn Res 2016;10(2):ZC13-6
3. Araya M, Morelli L, Reid G, Sanders M.E., Stanton C, Pineiro M. & Ben Embarek P. Guidelines for the evaluation of probiotics in food. Report of a Joint FAO/ WHO Working Group on drafting guidelines for the evaluation of probiotics in food, London, Ontario, Canada. Rome, Geneva, Food and Agriculture Organization of the United Nations and World Health Organization, 2002.
4. Singh VP, Sharma J, Babu S, Rizwanulla & Singla A. Role of probiotics in health and disease: a review. J Pak Med Assoc. 2013;63(2):253-7
5. Twetman. Are we ready for caries prevention through bacteriotherapy? Braz Oral Res. 2012;26(SpecIss 1):64-70
6. Marttinen A, Haukioja A, Karjalainen S, Nylund L, Satokari R, Öhman C, Holgerson P, Twetman S & Söderling E. Short-term consumption of probiotic lactobacilli has no effect on acid production of supragingival plaque. Clin Oral Investig. 2012;16(3):797-803.
7. Sidhu GK, Mantha S, Murthi S, Sura H, Kadaru P & Jngra JK. Evaluation of Lactobacillus and Streptococcus mutans by Addition of Probiotics in the form of Curd in the Diet. J Int Oral Health. 2015;7(7):85-9
8. Allaker R & Douglas CW. Non-convention al therapeutics for oral infections. Virulence. 2015;6(3):196-207
9. Iniesta M, Zurbriggen M, Montero E, Herrera D. Los probióticos y sus benefcios terapéuticos. Periodoncia y Osteointegración. 2011;21(3): 171-179
10. Madhwani T & McBain AJ. Bacteriological effects of a Lactobacillus reuteri probiotic on in vitro oral bioflms. Arch Oral Biol. 2011;56(11):1264-73
11. Hedayati-Hajikand T, Lundberg U, Eldh C & Twetman S. Effect of probiotic chewing tablets on early childhood caries – a randomized controlled trial. BMC Oral Health. 2015 Sep 24;15(1):112
12. Hedayati-Hajikand T, Lundberg U, Eldh C & Twetman S. Effect of probiotic chewing tablets on early childhood caries – a randomized controlled trial. BMC Oral Health. 2015 Sep 24;15(1):112
13. Ashwin D, Ke V, Taranath M, Ramagoni NK, Nara A & Sarpangala M. Effect of Probiotic Containing Ice-cream on Salivary Mutans Streptococci (SMS) Levels in Children of 6-12 Years of Age: A Randomized Controlled Double Blind Study with Six-months Follow Up. J Clin Diagn Res 2015;9(2):ZC06-9 doi: 10.7860/JCDR/2015/10942.5532. Epub 2015 Feb 1.
14. Toiviainen A, Jalasvuori H, Lahti E, Gursoy U, salminen S, Fontana M, Flannagan S, Eckert G, Kokaras A, Paster B & Söderling E. Impact of orally administered lozenges with Lactobacillus rhamnosus GG and Bifdobacterium animalis subsp. lactis BB-12 on the number of salivary mutans streptococci, amount of plaque, gingival inflammation and the oral microbiome in healthy adults. Clin Oral Investig. 2015;19(1):77-83
15. Rebolledo M, Rojas E, Salgado F. Efecto de dos probioticos que contienen cepas de Lactobacillus casei variedad rhamnosus y Lactobacillus johnsonii sobre el crecimiento in vitro de Streptococcus mutans. Int. J. Odontostomat. 2013;7(3):415-419
16. Schwendicke F, Horb K, Kneist S, Dörfer C & Paris S. Effects of heat-inactivated Bifdobacterium BB12 on cariogenicity of Streptococcus mutans in vitro. Arch Oral Biol. 2014 Dec;59(12):1384-90.
17. Vistoso A. Efecto del consumo de leche enriquecida con probióticos lactobacilos, en la incidencia de lesiones de caries en niños preescolares. [Tesis]. Santiago: Universidad de Chile. Facultad de Odontología; 2013
18. Moreno B. Efecto del consumo de leche con suplementos probióticos en la progresión de lesiones de caries en dientes temporales. [Tesis]. Santiago: Universidad de Chile. Facultad de Odontología; 2015
19. Nishihara T, Suzuki N, Yoneda M & Hirofuiji T. Effects of Lactobacillus salivarius-containing tablets on caries risk factors: a randomized open-label clinical trial. BMC Oral Health. 2014. 2;14:110
20. Terai T, Okumura T, Imai S, Nakao M, Yamaji K, Ito M, Nagata T, Kaneko K, Miyazaki K, Okada A, Nomura Y & Hanada N. Screening of Probiotic Candidates in Human Oral Bacteria for the Prevention of Dental Disease. PLoS One. 2015 Jun 8;10(6):e0128657
21. Pérez-Luyo A. Probióticos: Una nueva alternativa en la prevención de la caries dental? Rev Estomatol Herediana. 2008; 18(1):65-68.
22. Wattanarat O, Makeudom A, Sastraruji T, Piwat S, Tianviwat S, Teanpaisan R & Krisanaprakornkit S. Enhancement of salivary human neutrophil peptide 1-3 levels by probiotic supplementation. BMC Oral Health. 2015 Feb 10;15:19
23. Holz C, Alexander C, Balcke C, Moré M, Auinger A, Bauer M, Junker L, Grünwald J, Lang C & Pompejus M. Lactobacillus paracasei DSMZ16671 Reduces Mutans Streptococci: A Short-Term Pilot Study. Probiotics & Antimicro Proteins. (2013) 5:259–263
24. Teanpaisan R & Piwat S. Lactobacillus paracasei SD1, a novel probiotic, reduces mutans streptococci in human volunteers: a randomized placebo-controlled trial. Clin Oral Invest 2014;18:857–862
25. Lozano L. Efectividad de un yogur comercial con y sin cepas probióticas sobre el crecimiento de streptococcos mutans en saliva de niños de 3 a 5 años con caries, en la I.E. 81015 Carlos E. UDEDA Meza, Trujillo 2013. [Tesis]. Trujillo: Universidad Nacional de Trujillo. Facultad de Medicina. Escuela de Estomatología
26. Jalasvuori H, Haukioja A & Tenovuo J. Probiotic Lactobacillus reuteris trains ATCC PTA 5289 and ATCC 55730 differ in their cariogenic properties in vitro.
Arch Oral Biol. 2012;57(12):1633-8
27. Masdea L, kulik EM, Hauser-Gerspach I, Ramseier AM, Filippi A & Waltimo T. Antimicrobial activity of Streptococcus salivarius K12 on bacteria involved in oral malodour. Arch Oral Biol. 2012; 57(8):1041-1047.
28. Shino B, Peedikayil FC, Jaiprakash SR, Ahmed Bijapur G, Kottayi S & Jose D. Comparison of Antimicrobial Activity of Chlorhexidine, Coconut Oil, Probiotics, and Ketoconazole on Candida albicans Isolated in Children with Early Childhood Caries: An In Vitro Study. Scientifca (Cairo) 2016; 2016:7061587. doi:
10.1155/2016/7061587. Epub 2016 Mar 14
2. Srivastava S, Sabyasachi S, Kumari M & Mohd S. Effect of Probiotic Curd on Salivary pH and Streptococcus mutans: A Double Blind Parallel Randomized Controlled Trial. J Clin Diagn Res 2016;10(2):ZC13-6
3. Araya M, Morelli L, Reid G, Sanders M.E., Stanton C, Pineiro M. & Ben Embarek P. Guidelines for the evaluation of probiotics in food. Report of a Joint FAO/ WHO Working Group on drafting guidelines for the evaluation of probiotics in food, London, Ontario, Canada. Rome, Geneva, Food and Agriculture Organization of the United Nations and World Health Organization, 2002.
4. Singh VP, Sharma J, Babu S, Rizwanulla & Singla A. Role of probiotics in health and disease: a review. J Pak Med Assoc. 2013;63(2):253-7
5. Twetman. Are we ready for caries prevention through bacteriotherapy? Braz Oral Res. 2012;26(SpecIss 1):64-70
6. Marttinen A, Haukioja A, Karjalainen S, Nylund L, Satokari R, Öhman C, Holgerson P, Twetman S & Söderling E. Short-term consumption of probiotic lactobacilli has no effect on acid production of supragingival plaque. Clin Oral Investig. 2012;16(3):797-803.
7. Sidhu GK, Mantha S, Murthi S, Sura H, Kadaru P & Jngra JK. Evaluation of Lactobacillus and Streptococcus mutans by Addition of Probiotics in the form of Curd in the Diet. J Int Oral Health. 2015;7(7):85-9
8. Allaker R & Douglas CW. Non-convention al therapeutics for oral infections. Virulence. 2015;6(3):196-207
9. Iniesta M, Zurbriggen M, Montero E, Herrera D. Los probióticos y sus benefcios terapéuticos. Periodoncia y Osteointegración. 2011;21(3): 171-179
10. Madhwani T & McBain AJ. Bacteriological effects of a Lactobacillus reuteri probiotic on in vitro oral bioflms. Arch Oral Biol. 2011;56(11):1264-73
11. Hedayati-Hajikand T, Lundberg U, Eldh C & Twetman S. Effect of probiotic chewing tablets on early childhood caries – a randomized controlled trial. BMC Oral Health. 2015 Sep 24;15(1):112
12. Hedayati-Hajikand T, Lundberg U, Eldh C & Twetman S. Effect of probiotic chewing tablets on early childhood caries – a randomized controlled trial. BMC Oral Health. 2015 Sep 24;15(1):112
13. Ashwin D, Ke V, Taranath M, Ramagoni NK, Nara A & Sarpangala M. Effect of Probiotic Containing Ice-cream on Salivary Mutans Streptococci (SMS) Levels in Children of 6-12 Years of Age: A Randomized Controlled Double Blind Study with Six-months Follow Up. J Clin Diagn Res 2015;9(2):ZC06-9 doi: 10.7860/JCDR/2015/10942.5532. Epub 2015 Feb 1.
14. Toiviainen A, Jalasvuori H, Lahti E, Gursoy U, salminen S, Fontana M, Flannagan S, Eckert G, Kokaras A, Paster B & Söderling E. Impact of orally administered lozenges with Lactobacillus rhamnosus GG and Bifdobacterium animalis subsp. lactis BB-12 on the number of salivary mutans streptococci, amount of plaque, gingival inflammation and the oral microbiome in healthy adults. Clin Oral Investig. 2015;19(1):77-83
15. Rebolledo M, Rojas E, Salgado F. Efecto de dos probioticos que contienen cepas de Lactobacillus casei variedad rhamnosus y Lactobacillus johnsonii sobre el crecimiento in vitro de Streptococcus mutans. Int. J. Odontostomat. 2013;7(3):415-419
16. Schwendicke F, Horb K, Kneist S, Dörfer C & Paris S. Effects of heat-inactivated Bifdobacterium BB12 on cariogenicity of Streptococcus mutans in vitro. Arch Oral Biol. 2014 Dec;59(12):1384-90.
17. Vistoso A. Efecto del consumo de leche enriquecida con probióticos lactobacilos, en la incidencia de lesiones de caries en niños preescolares. [Tesis]. Santiago: Universidad de Chile. Facultad de Odontología; 2013
18. Moreno B. Efecto del consumo de leche con suplementos probióticos en la progresión de lesiones de caries en dientes temporales. [Tesis]. Santiago: Universidad de Chile. Facultad de Odontología; 2015
19. Nishihara T, Suzuki N, Yoneda M & Hirofuiji T. Effects of Lactobacillus salivarius-containing tablets on caries risk factors: a randomized open-label clinical trial. BMC Oral Health. 2014. 2;14:110
20. Terai T, Okumura T, Imai S, Nakao M, Yamaji K, Ito M, Nagata T, Kaneko K, Miyazaki K, Okada A, Nomura Y & Hanada N. Screening of Probiotic Candidates in Human Oral Bacteria for the Prevention of Dental Disease. PLoS One. 2015 Jun 8;10(6):e0128657
21. Pérez-Luyo A. Probióticos: Una nueva alternativa en la prevención de la caries dental? Rev Estomatol Herediana. 2008; 18(1):65-68.
22. Wattanarat O, Makeudom A, Sastraruji T, Piwat S, Tianviwat S, Teanpaisan R & Krisanaprakornkit S. Enhancement of salivary human neutrophil peptide 1-3 levels by probiotic supplementation. BMC Oral Health. 2015 Feb 10;15:19
23. Holz C, Alexander C, Balcke C, Moré M, Auinger A, Bauer M, Junker L, Grünwald J, Lang C & Pompejus M. Lactobacillus paracasei DSMZ16671 Reduces Mutans Streptococci: A Short-Term Pilot Study. Probiotics & Antimicro Proteins. (2013) 5:259–263
24. Teanpaisan R & Piwat S. Lactobacillus paracasei SD1, a novel probiotic, reduces mutans streptococci in human volunteers: a randomized placebo-controlled trial. Clin Oral Invest 2014;18:857–862
25. Lozano L. Efectividad de un yogur comercial con y sin cepas probióticas sobre el crecimiento de streptococcos mutans en saliva de niños de 3 a 5 años con caries, en la I.E. 81015 Carlos E. UDEDA Meza, Trujillo 2013. [Tesis]. Trujillo: Universidad Nacional de Trujillo. Facultad de Medicina. Escuela de Estomatología
26. Jalasvuori H, Haukioja A & Tenovuo J. Probiotic Lactobacillus reuteris trains ATCC PTA 5289 and ATCC 55730 differ in their cariogenic properties in vitro.
Arch Oral Biol. 2012;57(12):1633-8
27. Masdea L, kulik EM, Hauser-Gerspach I, Ramseier AM, Filippi A & Waltimo T. Antimicrobial activity of Streptococcus salivarius K12 on bacteria involved in oral malodour. Arch Oral Biol. 2012; 57(8):1041-1047.
28. Shino B, Peedikayil FC, Jaiprakash SR, Ahmed Bijapur G, Kottayi S & Jose D. Comparison of Antimicrobial Activity of Chlorhexidine, Coconut Oil, Probiotics, and Ketoconazole on Candida albicans Isolated in Children with Early Childhood Caries: An In Vitro Study. Scientifca (Cairo) 2016; 2016:7061587. doi:
10.1155/2016/7061587. Epub 2016 Mar 14