Keywords
breathing disorders, inhalers, xerostomia, oral pathology
How to Cite
Problemas de salud bucal relacionados al uso de medicamentos por vía inhalatoria en trastornos respiratorios. (2012). Odontoestomatología, 14(20), 4-16. https://odon.edu.uy/ojs/index.php/ode/article/view/198
Abstract
The children prevalence of non-infectious respiratory disease in Uruguay is high. The medical management of this disease might be associated with adverse effects in oral health. The aim of this study was to increase the knowledge regarding asthma in children and adolescents, to review the medicines and therapeutic devices used and to depict possible associations between the use of inhalation therapy and specific oral diseases. The review of the literature showed that the use of inhalatory therapy for noninfectious respiratory disorders is associated with side effects such as tooth erosion, dental caries, gingivitis, halitosis, candidiasis and xerostomia. The survey of patients from the Pereira Rossell Hospital Centre showed a positive correlation between the available scientific evidence and the clinical observations that we made. Taking into account this background, it is important that the health care team recognizes people who use inhalers as a high risk potential for the development of oral pathologies, emphasizing the need for preventive-educative specific programs. Health care of patients with noninfectious respiratory diseases requires a multidisciplinary approach.
References
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Irache J.M. Vías aéreas o respiratorias. Formas de administración. Universidad de Navarra. Disponible en: http://www. unav.es/adi/UserFiles/File/80962510/12pulmonar.pdf Acceso el 03.02.2012. [ Links ]
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Delgado N. y cols. Salud bucal en pacientes asmáticos. Revista Electrónica de las Ciencias Médicas en Cien-fuegos [en línea] 2003; 1(1):23-30 [Fecha de acceso: 01.09.2012] Disponible en: http://dialnet.unirioja.es/servlet/ articulo?codigo=2866809 [ Links ]
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Reddy D, Hedge A, Munich A. Dental caries status of children with bronchial asthma. J.Clinic Pediatric Dent, 2003 spring, 27(3):293-5. [ Links ]
Yokohama H, Nakajima Y, Yamamura Y.Investigation of mouth washing after inhaled corticosteroids in the patiens. YakugakuZasshi [en línea] 2005 may; 125(5):455-61 [Fecha de acceso: 24.09.2012] Disponible en: https://www.jstage.jst.go.jp/article/ yakushi/125/5/125_5_455/_article
[ Links ]
Fukushima C, Matsuse H, Saeki S, Machida I, Kondo Y, Kohno S.Salivary IgA and oral candidiasis in asmathics patients treated with inhaled corticosteroid. Second Department of Internal Medicine, Nagasaki, Japan. J. Asthma, 2005 sep; 42 (7):601-4 [ Links ]
Eloot A, Vanobbergen J, Martens L. Oral health in asthmatic children: a dose-reponse study. Rev Belge Med Dent (1984). 2004;59(2):130-7. [ Links ]
Lenander-Lumikari M, Laurikainen K, Kuusisto P, Vilja P. Stimulated salivary low rate and composition in asthmatic and non asthmatic adults. Arch Oral Biol 1998 feb; 43(2):151-6 [ Links ]
Sernaqué Marroquín, RJ. Variación del lujo saliva en niños asmáticos por uso de inhaladores beta-2 adrenérgicos [Tesis]. Universidad Mayor de San Marcos, Facultad de Odontología, EAP de Odont., Lima-Perú, 2004. [Fecha de acceso: 01.09.2012] Disponible en: http://www. cybertesis.edu.pe/sisbib/2004/sernaque_ mr/pdf/sernaque_mr.pdf [ Links ]
Laurikainen K, Kuusisto P. Comparison of the oral health status and salivary low rate of asthmatic patients with those of non asthmatic adults. Results of a pilot study. Allergy 1998 mar; 53(3):316-9 [ Links ]
Tootla R, Toumba KJ, Duggal MS. An evaluation of the acidogenic potential of asthma inhalers. Arch Oral Biol 2004 Apr;49(4):275-8 [ Links ]
Sag C, Dzden FO, Acikgoz G, Anlar FY. The efects of combination treatment with a long-acting beta2-agonist and a corticosteroid on salivary low rate, secretory immunoglobulin A and oral health in children and adolescents with mode rated asthma: a 1 month, single-blind clinical study. Clin Ther. 2007 Oct;29(10):223642 [ Links ]
Randell T, Donaghue K, Ambler G. Safety of the newer inhaled corticosteroid in childhood asthma. Paediatric drugs 2003; 5(7):481-504. [ Links ]
Cintra C, Formin A, Pastorino A, Castro A, Jacob C. Alteracöes da cavidade bucal emcriancas asmática. Rev. Bras. Alergiainmunopatol; 24(1):33-36, jan-fev 2001. [ Links ]
Kargul B, Tanboga I, Ergeneli S. Inhaler medicament effects on saliva and plaque pH in asmathic children. J Pediatr Dent 1998 winter; 22(2):137-40. [ Links ]
The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Worldwide variations in the prevalence of asthma symptoms: the International Study of Asthma and Allergies in Childhood (ISAAC). Eur Respir J 1998; 12: 315-35 [ Links ]
Equipo respirar, El asma la epidemia del siglo 21. [Fecha de acceso: 25.11.2011] Disponible en: http://www.respirar.org/ respirar/epidemiologia/la-epidemia-delsiglo-xxi.html [ Links ]
Meneghello J. Pediatría, 4ªed. v1. Santiago: Mediterráneo, 1991 [ Links ]
Gentile Ramos I. y cols. Semiología Pediátrica.Tomo II Montevideo: Oficina del Libro AEM, 1995 [ Links ]
Maggi R. y cols. Clínica Pediátrica. Tomo 6. Montevideo: Oficina del Libro-AEM, 1993 [ Links ]
Ucros Rodríguez S., Mejía Gaviria N. Guía de pediatría práctica basada en la evidencia, 2°ed. Bogotá: Ed. Médica Panamericana, 2010 [ Links ]
Villoria C. Efectos a nivel dentario en niños asmáticos con uso continuo de corticoides inhalados o tomados. Revisión de la literatura. Acta Odontol Venez 2007: 45 (1): 113-115. [ Links ]
Mc Derra E, Pollard M, Curzan M. The dental status of asthmatic British School children. PediatricDent 1998; 20(4):281-7 [ Links ]
Irache J.M. Vías aéreas o respiratorias. Formas de administración. Universidad de Navarra. Disponible en: http://www. unav.es/adi/UserFiles/File/80962510/12pulmonar.pdf Acceso el 03.02.2012. [ Links ]
Giner J, Basualdo LV, Casan P, Hernandez C, Macian V, Martinez I, Mengibar A. Normativa sobre la utilización de fármacos inhalados. Normativa SEPAR. Arch. Bronconeumol. 2000; 36:34-43 [ Links ]
Generalitat de Catalunya, Departament de Salut. Trastornos dentales inducidos por fármacos. Bulletí de farmacovigilancia de Catalunya 2009; l7(1)[Fecha de acceso: 01.09.2012] Disponible en:http://www.sld.cu/galerias/pdf/servicios/medicamentos/trastornos_dentales_inducidos_por_farmacos.pdf [ Links ]
Bijwerkingen Centrum Lareb, Netherland. Salbutamol inhalation and dental caries. Netherland Pharmacovigilance Centre, mei 2008. [ Links ]
Delgado N. y cols. Salud bucal en pacientes asmáticos. Revista Electrónica de las Ciencias Médicas en Cien-fuegos [en línea] 2003; 1(1):23-30 [Fecha de acceso: 01.09.2012] Disponible en: http://dialnet.unirioja.es/servlet/ articulo?codigo=2866809 [ Links ]
Ersin NK, Gülen F, Eronat N, Cogulu D, Demir E, Tanac R.Oral and dental manifestations of young asthmatics related to medication, severity and duration of condition. Department of Pedodontics, Ege University, Bornova-Jzmir, Turkey. Pediatric Int, 2006 dec; 48(6):549-54. [ Links ]
Reddy D, Hedge A, Munich A. Dental caries status of children with bronchial asthma. J.Clinic Pediatric Dent, 2003 spring, 27(3):293-5. [ Links ]
Yokohama H, Nakajima Y, Yamamura Y.Investigation of mouth washing after inhaled corticosteroids in the patiens. YakugakuZasshi [en línea] 2005 may; 125(5):455-61 [Fecha de acceso: 24.09.2012] Disponible en: https://www.jstage.jst.go.jp/article/ yakushi/125/5/125_5_455/_article
[ Links ]
Fukushima C, Matsuse H, Saeki S, Machida I, Kondo Y, Kohno S.Salivary IgA and oral candidiasis in asmathics patients treated with inhaled corticosteroid. Second Department of Internal Medicine, Nagasaki, Japan. J. Asthma, 2005 sep; 42 (7):601-4 [ Links ]
Eloot A, Vanobbergen J, Martens L. Oral health in asthmatic children: a dose-reponse study. Rev Belge Med Dent (1984). 2004;59(2):130-7. [ Links ]
Lenander-Lumikari M, Laurikainen K, Kuusisto P, Vilja P. Stimulated salivary low rate and composition in asthmatic and non asthmatic adults. Arch Oral Biol 1998 feb; 43(2):151-6 [ Links ]
Sernaqué Marroquín, RJ. Variación del lujo saliva en niños asmáticos por uso de inhaladores beta-2 adrenérgicos [Tesis]. Universidad Mayor de San Marcos, Facultad de Odontología, EAP de Odont., Lima-Perú, 2004. [Fecha de acceso: 01.09.2012] Disponible en: http://www. cybertesis.edu.pe/sisbib/2004/sernaque_ mr/pdf/sernaque_mr.pdf [ Links ]
Laurikainen K, Kuusisto P. Comparison of the oral health status and salivary low rate of asthmatic patients with those of non asthmatic adults. Results of a pilot study. Allergy 1998 mar; 53(3):316-9 [ Links ]
Tootla R, Toumba KJ, Duggal MS. An evaluation of the acidogenic potential of asthma inhalers. Arch Oral Biol 2004 Apr;49(4):275-8 [ Links ]
Sag C, Dzden FO, Acikgoz G, Anlar FY. The efects of combination treatment with a long-acting beta2-agonist and a corticosteroid on salivary low rate, secretory immunoglobulin A and oral health in children and adolescents with mode rated asthma: a 1 month, single-blind clinical study. Clin Ther. 2007 Oct;29(10):223642 [ Links ]
Randell T, Donaghue K, Ambler G. Safety of the newer inhaled corticosteroid in childhood asthma. Paediatric drugs 2003; 5(7):481-504. [ Links ]
Cintra C, Formin A, Pastorino A, Castro A, Jacob C. Alteracöes da cavidade bucal emcriancas asmática. Rev. Bras. Alergiainmunopatol; 24(1):33-36, jan-fev 2001. [ Links ]
Kargul B, Tanboga I, Ergeneli S. Inhaler medicament effects on saliva and plaque pH in asmathic children. J Pediatr Dent 1998 winter; 22(2):137-40. [ Links ]